Results 71 to 80 of about 4,144,807 (197)

Cytomegalovirus in Bronchoalveolar Lavage Fluid: A Predictor of Outcome in Immunocompromised Patients

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Cytomegalovirus (CMV) is a prevalent herpesvirus that remains typically asymptomatic in immunocompetent individuals but can cause severe, potentially life‐threatening disease in immunocompromised patients. This study assessed the impact of CMV‐associated lower respiratory tract infections (LRTIs), diagnosed by polymerase chain reaction (PCR ...
Theodora Zouvani, Meropi Karakioulaki, Kathleen Jahn, Sebastian Fähndrich, Björn C. Frye, Leticia Grize, Eleni Papakonstantinou, Hartmut Hengel, Karoline Leuzinger, Hans H. Hirsch, Daiana Stolz   +10 more
wiley   +1 more source

Evaluation of Amplification Targets for the Specific Detection of Bordetella pertussis Using Real-Time Polymerase Chain Reaction

Canadian Journal of Infectious Diseases and Medical Microbiology, 2014
BACKGROUND: Bordetella pertussis infections continue to be a major public health challenge in Canada. Polymerase chain reaction (PCR) assays to detect B pertussis are typically based on the multicopy insertion sequence IS481, which offers
Mohammad Rubayet Hasan, Rusung Tan, Ghada N Al-Rawahi, Eva Thomas, Peter Tilley   +4 more
doaj   +1 more source

Identification of Molecular Pathways Underlying Mn(II) Oxidation in Pseudomonas resinovorans

Environmental Microbiology, Volume 28, Issue 10, October 2026.
Transposon mutagenesis in biofilter‐associated Pseudomonas resinovorans MOB‐513 identifies a c‐di‐GMP‐dependent regulatory network involving type IV pili, two‐component systems, and diguanylate cyclases that controls Mn(II) oxidation and biofilm formation, providing new insight into microbial manganese cycling and biofilter performance.
Ainelén Piazza, Lucia Parra, Marilina Gaffuri, Jacob G. Malone, Jorgelina Ottado, Natalia Gottig   +5 more
wiley   +1 more source

Host and Environmental Factors Outweigh Pathogen in Shaping Skin Microbiome of a Threatened Andean Amphibian Community

Molecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT The fungal pathogen Batrachochytrium dendrobatidis (Bd) has driven severe amphibian declines across the Neotropics, yet some species persist under enzootic pathogen conditions following epizootics. We investigated whether skin bacterial communities and host mucosome activity contributed to the persistence of seven amphibian species in a once ...
Claudia Lansac, Ignacio De la Riva, Marta Miñarro, Amadeus Plewnia, Ana V. Longo, Patricia A. Burrowes   +5 more
wiley   +1 more source

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates

Toxins, 2017
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Valérie Bouchez, Thibaut Douché, Mélody Dazas, Sophie Delaplane, Mariette Matondo, Julia Chamot-Rooke, Nicole Guiso   +6 more
doaj   +1 more source

Phenotypic expression of the gene‐for‐gene interaction in plant pathogenic bacteria: An implication for resistance to bacterial diseases by plants

Agrosystems, Geosciences &Environment, Volume 9, Issue 3, September 2026.
Abstract Plant pathogenic bacteria cause massive losses in agriculture and damage to natural plant habitats. Bacterial pathogens not only reduce crop production, but they also reduce crop quality by releasing toxins into the environment. Pathogenic bacteria that invade plant tissues must overcome the plant's defense mechanisms. Plants possess an innate
Muluken Getahun, Zelalem Bekeko
wiley   +1 more source

Evolution of Bordetellae from Environmental Microbes to Human Respiratory Pathogens: Amoebae as a Missing Link

Frontiers in Cellular and Infection Microbiology, 2017
The genus Bordetella comprises several bacterial species that colonize the respiratory tract of mammals. It includes B. pertussis, a human-restricted pathogen that is the causative agent of Whooping Cough.
Dawn L. Taylor-Mulneix, Illiassou Hamidou Soumana, Bodo Linz, Eric T. Harvill   +3 more
doaj   +1 more source

The Baboon as a Model to Study Human Health and Complex Disease

American Journal of Primatology, Volume 88, Issue 9, September 2026.
Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley   +1 more source

Protein–Protein Interactions Between Peptidoglycan, Lipopolysaccharide, and Phospholipid Biosynthesis Enzymes in Escherichia coli

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
MurA, the first peptidoglycan biosynthesis enzyme, interacts with essential proteins involved in lipopolysaccharide and phospholipid biogenesis and is associated with the LapB interactome. Gram‐negative bacteria are protected by a three‐layered cell envelope and must tightly coordinate the biosynthesis of phospholipids (PL), peptidoglycan (PG) and ...
Lea‐Janina Tilg, Sophia Weber, Hannah Bille, Anna‐Maria Möller, Franz Narberhaus   +4 more
wiley   +1 more source

TRANSCRIPTIONAL REGULATION AND PROTECTIVE EFFICACY OF BORDETELLA COLONIZATION FACTOR A (BcfA) IN BORDETELLA INFECTIONS

, 2009
To successfully colonize their mammalian hosts many bacteria produce multiple virulence factors that play essential roles in disease processes and pathogenesis.
Sukumar, Neelima
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