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Borna Disease Virus Assembles Porous Cage-like Viral Factories in the Nucleus. [PDF]
J Biol Chem, 2016 Hirai Y +5 more
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Borna disease virus and infection in humans
Frontiers in Bioscience - Landmark, 2002Borna disease virus (BDV) is a nonsegmented, negative-, single-stranded, highly neurotropic RNA virus with noncytolytic replication in the central nervous system. This virus causes neurological and behavioral disturbances primarily in horses and sheep, in addition to a variety of other vertebrate animal species and in laboratory animal models.
Madiha Ibrahim, Keizo Tomonaga
exaly +3 more sources
The immunopathogenesis of Borna disease virus infection
Frontiers in Bioscience - Landmark, 2002Borna disease virus (BDV) infection represents an excellent model system to study immunopathological mechanisms based on a T cell-mediated immune reaction in the central nervous system. The single-stranded RNA Borna disease virus, a member of Bornaviridae in the order of Mononegavirale, lacks cytopathogenicity both in vitro and in vivo.
Oliver Planz +2 more
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Veterinary Clinics of North America: Equine Practice, 2000
Borna disease is a sporadically occurring, progressive viral polioencephalomyelitis that primarily affects horses and sheep. The etiological agent, Borna disease virus (BDV), is an enveloped, single-stranded RNA virus that has been classified in the new virus family Bornaviridae within the order Mononegavirales.
J A, Richt, A, Grabner, S, Herzog
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Borna disease is a sporadically occurring, progressive viral polioencephalomyelitis that primarily affects horses and sheep. The etiological agent, Borna disease virus (BDV), is an enveloped, single-stranded RNA virus that has been classified in the new virus family Bornaviridae within the order Mononegavirales.
J A, Richt, A, Grabner, S, Herzog
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Journal of Neurovirology, 2002
Borna disease virus, a negative-strand RNA virus, infects a wide variety of warm-blooded animals. Depending on the age of the host and the integrity of its immune response, infection may be asymptomatic or cause a broad spectrum of behavioral disorders.
Mady, Hornig +2 more
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Borna disease virus, a negative-strand RNA virus, infects a wide variety of warm-blooded animals. Depending on the age of the host and the integrity of its immune response, infection may be asymptomatic or cause a broad spectrum of behavioral disorders.
Mady, Hornig +2 more
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Neurotransmitter abnormalities in Borna disease
Brain Research, 1988Borna disease (BD) agent is an infectious pathogen that causes progressive central nervous system (CNS) dysfunction in a wide range of vertebrate hosts. The course of BD in adult rats is biphasic. The acute phase is characterized by aggressive behavior and inflammatory cell infiltrates in brain.
W I, Lipkin +5 more
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Immunopathogenesis of Borna Disease
1995Diseases of the central nervous system are fearsome conditions due to their deleterious effects on physical and mental functions. In addition to acute diseases caused by viruses and bacteria infecting the meninges and the brain, disturbances of motility, disorders in sensory functions, behavioral abnormalities, personality changes and chronic debility ...
L, Stitz, B, Dietzschold, K M, Carbone
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Dementia and Borna Disease Virus
Dementia and Geriatric Cognitive Disorders, 1997Human Borna disease virus (BDV) infection has been reported to be a threat to mental health [1]. BDV is an unclassified, nonsegmented negative sense single-stranded RNA virus which naturally infects horses, cattle, cats and sheep [2, 3]. Infection causes disturbances in behavior and cognitive function [1].
T, Igata +7 more
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Borna disease virus and schizophrenia
Psychiatry Research, 1995The development of a new serological assay method to detect antibodies in human sera recognizing Borna disease virus (BDV) proteins and a clinical pilot study are presented. Psychiatric patients from a schizophrenia research clinic in Baltimore, Maryland, were examined for antibodies to BDV antigen with traditional indirect immunofluorescence assays ...
R W, Waltrip +7 more
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Comparative Immunology, Microbiology and Infectious Diseases, 1978
Abstract Borna is an ideal model for the study of the pathogenesis of slow virus diseases. Our present knowledge of the nature of the agent, the immunology, the pathogenesis, the different courses of infection and diagnosis is described. The wide host and cell spectrum of Borna virus leads one to suppose that Borna infections are more widespread ...
A, Mayr, K, Danner
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Abstract Borna is an ideal model for the study of the pathogenesis of slow virus diseases. Our present knowledge of the nature of the agent, the immunology, the pathogenesis, the different courses of infection and diagnosis is described. The wide host and cell spectrum of Borna virus leads one to suppose that Borna infections are more widespread ...
A, Mayr, K, Danner
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