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Borna Disease in a Dog in Japan
Journal of Comparative Pathology, 2002Borna disease (BD) was diagnosed in a 3-year-old male Welsh corgi suffering from a severe and acute progressive disorder of the central nervous system. Histopathologically, neuronal lesions were characterized by a non-suppurative encephalomyelitis dominated by large perivascular cuffs consisting of lymphocytes, macrophages and plasma cells; also ...
M, Okamoto +7 more
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Immune-Mediated Pathogenesis of Borna Disease
Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1988Borna disease is an endemic progressive encephalomyelitis of horses and sheep prevalent in central Europe. A wide variety of animal species, ranging from chickens to primates can be infected experimentally with the causative virus, which is only poorly characterized. Furthermore, BD virus-specific antibodies have been detected in sera and cerebrospinal
R, Rott, S, Herzog, J, Richt, L, Stitz
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Borna disease virus is not sensitive to amantadine
Archives of Virology, 1997Successful inhibition of Borna disease virus (BDV) by amantadine in cultured cells and in an infected human individual has been reported [Bode et al. (1997) Lancet 349: 178-179]. We now found that infection of monkey Vero cells by laboratory strains of BDV was not influenced by amantadine under conditions that reduced the yields of influenza A virus by
Hallensleben, Wiebke +2 more
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Immunitat und Infektion, 1989
Using Borna disease as a model, the consequences of persistent virus infections of the central nervous system, in particular of "slow virus diseases", are briefly described. Both latent and active forms of the disease have much in common with chronically progressive diseases of the central nervous system in animals and man which have until now remained
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Using Borna disease as a model, the consequences of persistent virus infections of the central nervous system, in particular of "slow virus diseases", are briefly described. Both latent and active forms of the disease have much in common with chronically progressive diseases of the central nervous system in animals and man which have until now remained
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Molecular characterization of the borna disease agent
Virology, 1990Borna disease (BD) is a neurologic syndrome characterized by profound disturbances in behavior and the accumulation of specific antigens in limbic system neurons. The potency of brain homogenates from animals with BD to cause disease in normal animals is reduced by exposure to detergents.
J C, de la Torre +2 more
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A Borna-Like Disease of Ostriches in Israel
1995Wild ostriches were once part of the indigenous fauna of the Middle East. The earliest archaeological artifacts date from the Chalcolithic era (4000 B.C.E.) or earlier (Grigson 1987; Paz 1987), when Struthio camelus syriacus, an extinct subspecies, inhabited the Fertile Crescent. All the other extant subspecies are native to Africa.
M, Malkinson +3 more
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[Immunopathogenesis of Borna disease].
Tierarztliche Praxis, 1991An overview of the pathogenesis of Borna disease (BD) in rats as a model for the naturally occurring infection in horses and sheep is presented. Our findings revealed a virus infection in which a virus-specific T cell-mediated immune response leads to disease. The immune cells capable of mediating this immunopathological reaction were defined as helper/
L, Stitz, J A, Richt, R, Rott
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2016
The neurotropic virus, Borna disease virus (BDV), a member of a group of nonsegmented, negative strand ribonucleic acid (RNA) viruses (order Mononegavirales), infects warm-blooded animal species. Infection among mammals may be asymptomatic, produce neurobehavioral abnormalities, or result in fatal meningoencephalitis.
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The neurotropic virus, Borna disease virus (BDV), a member of a group of nonsegmented, negative strand ribonucleic acid (RNA) viruses (order Mononegavirales), infects warm-blooded animal species. Infection among mammals may be asymptomatic, produce neurobehavioral abnormalities, or result in fatal meningoencephalitis.
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Natural and Experimental Borna Disease in Animals
1995Borna disease (BD) is a transmissible, progressive polioencephalomyelitis of horses and sheep, which are the main natural hosts. It occurs sporadically in endemic areas of Germany and Switzerland, while its presence in other countries has not been fully substantiated.
R, Rott, H, Becht
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