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Borna disease virus and schizophrenia
Psychiatry Research, 1995The development of a new serological assay method to detect antibodies in human sera recognizing Borna disease virus (BDV) proteins and a clinical pilot study are presented. Psychiatric patients from a schizophrenia research clinic in Baltimore, Maryland, were examined for antibodies to BDV antigen with traditional indirect immunofluorescence assays ...
R W, Waltrip +7 more
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Borna disease: virus-induced neurobehavioral disease pathogenesis
Current Opinion in Microbiology, 2001Studies of the pathogenesis of neurobehavioral diseases following Borna disease virus infections have been increasing rapidly over the past ten years. Recent major advances have included a report of vertical transmission of the virus in its natural host, the horse, and a report of isolation of a novel variant, No/98, in that same species.
K M, Carbone +3 more
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Borna disease virus infection in cats
The Veterinary Journal, 2014Bornaviruses are known to cause neurological disorders in a number of animal species. Avian Bornavirus (ABV) causes proventricular dilatation disease (PDD) in birds and Borna disease virus (BDV) causes Borna disease in horses and sheep. BDV also causes staggering disease in cats, characterised by ataxia, behavioural changes and loss of postural ...
Jonas Johansson, Wensman +3 more
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Immunitat und Infektion, 1989
Using Borna disease as a model, the consequences of persistent virus infections of the central nervous system, in particular of "slow virus diseases", are briefly described. Both latent and active forms of the disease have much in common with chronically progressive diseases of the central nervous system in animals and man which have until now remained
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Using Borna disease as a model, the consequences of persistent virus infections of the central nervous system, in particular of "slow virus diseases", are briefly described. Both latent and active forms of the disease have much in common with chronically progressive diseases of the central nervous system in animals and man which have until now remained
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2016
The neurotropic virus, Borna disease virus (BDV), a member of a group of nonsegmented, negative strand ribonucleic acid (RNA) viruses (order Mononegavirales), infects warm-blooded animal species. Infection among mammals may be asymptomatic, produce neurobehavioral abnormalities, or result in fatal meningoencephalitis.
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The neurotropic virus, Borna disease virus (BDV), a member of a group of nonsegmented, negative strand ribonucleic acid (RNA) viruses (order Mononegavirales), infects warm-blooded animal species. Infection among mammals may be asymptomatic, produce neurobehavioral abnormalities, or result in fatal meningoencephalitis.
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Borna disease virus and deficit schizophrenia
Acta Neuropsychiatrica, 2003Background:It is controversial whether Borna disease virus (BDV) infects humans and causes psychiatric disorders.Objectives:The relationship between BDV infection and schizophrenia with deficit syndrome was investigated.Study design:Using the Schedule for the Deficit Syndrome, 62 schizophrenic in-patients were selected from three psychiatric hospitals.
Yong-Ku, Kim +9 more
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Immune-Mediated Pathogenesis of Borna Disease
Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1988Borna disease is an endemic progressive encephalomyelitis of horses and sheep prevalent in central Europe. A wide variety of animal species, ranging from chickens to primates can be infected experimentally with the causative virus, which is only poorly characterized. Furthermore, BD virus-specific antibodies have been detected in sera and cerebrospinal
R, Rott, S, Herzog, J, Richt, L, Stitz
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Borna disease in naturally infected cattle
Journal of Comparative Pathology, 1994Based on the immunohistochemical demonstration of viral antigen and on the histological brain lesions, Borna disease was diagnosed in a cow and a bull which had suffered from a severe, subacute progressive disorder of the central nervous system. Virus-specific antigen was characteristically localized in neurons, predominantly in the perikaryon and ...
Caplazi, P +4 more
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Molecular Biology of Borna Disease Virus
1995Originally described in the early nineteenth century as a fatal encephalitis in horses, Borna disease (BD) has become an extraordinarily valuable model for the study of both molecular mechanisms and biological consequences of persistent virus infection in the CNS (Nicolau and Galloway 1928; Zwick 1939, this volume).
T, Briese, W I, Lipkin, J C, de la Torre
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Some Pathogenetic Aspects of Borna Disease
1983Publisher Summary Borna disease (BD) is a chronic encephalomyelitis occurring naturally in horses and sheep. It is characterized by a long incubation period and a progressive development with gradual loss of coordination and certain sensory afflictions. Histopathological lesions are only seen in the nervous system.
R, Rott, K, Frese
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