Results 61 to 70 of about 9,174 (203)

Borna disease virus and psychiatry

European Psychiatry, 2001
Borna disease virus (BDV), a noncytolytic neurotropic nonsegmented negative-stranded RNA virus with a wide geographic distribution, infects several vertebrate animal species and causes an immune-mediated central nervous system (CNS) disease with various manifestations, depending on both host and viral factors.
O, Taieb, J M, Baleyte, P, Mazet, A M, Fillet   +3 more
openaire   +2 more sources

Genomic and epigenomic insights into purkinje and granule cells in Alzheimer's disease‐related dementia using single‐nucleus multiome analysis

Alzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Recent advances in single‐cell/nuclei multiome technology have enabled simultaneous profiling of gene expression and chromatin accessibility from the same nuclei, providing opportunities to interrogate the regulatory underpinnings responsible for Alzheimer's disease (AD) relevant transcriptomic and epigenomic features in a cell type‐
Feixiong Cheng, Yayan Feng, Margaret E Flanagan, Borna Bonakdarpour, Jeffrey L. Cummings   +4 more
wiley   +1 more source

Within host RNA virus persistence : mechanisms and consequences [PDF]

, 2017
RER is funded by the Wellcome Trust, UK (Grant 101788/Z/13/Z) and DEG by US National Institutes of Health (R01 NS038932).In a prototypical response to an acute viral infection it would be expected that the adaptive immune response would eliminate all ...
Griffin, Diane E., Randall, Richard E.
core   +1 more source

Rustrela Virus-Associated Encephalomyelitis (‘Staggering Disease’) in Cats from Eastern Austria, 1994–2016

Viruses, 2023
Clinical cases of ‘staggering disease’, a nonsuppurative encephalomyelitis associated with gait abnormalities in cats, have been documented for decades in Sweden. In Austria, an increased incidence was observed in the 1990s. Only recently, rustrela virus
Viktoria Weiss, Pia Weidinger, Julia Matt, Christiane Weissenbacher-Lang, Norbert Nowotny, Herbert Weissenböck   +5 more
doaj   +1 more source

Neurotrophic factor expression after CNS viral injury produces enhanced sensitivity to psychostimulants : potential mechanism for addiction vulnerability [PDF]

, 2000
Hypothesized risk factors for psychostimulant, amphetamine, and cocaine abuse include dopamine (DA) receptor polymorphisms, HIV infection, schizophrenia, drug-induced paranoias, and movement disorders; however, the molecular, cellular, and biochemical ...
Briese, Thomas, Horscroft, Nigel, Kadota, Tomoko, Koob, George F., Lipkin, W. Ian, Parsons, Loren H., Solbrig, Marylou V.   +6 more
core   +2 more sources

Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews. [PDF]

PLoS ONE, 2015
Many RNA viruses arise from animal reservoirs, namely bats, rodents and insectivores but mechanisms of virus maintenance and transmission still need to be addressed.
Daniel Nobach, Manon Bourg, Sibylle Herzog, Hildburg Lange-Herbst, Jorge A Encarnação, Markus Eickmann, Christiane Herden   +6 more
doaj   +1 more source

COVID‐19 Vaccine Effectiveness Against Hospitalization in Older Adults, VEBIS Hospital Network, Europe, September 2024–May 2025

Influenza and Other Respiratory Viruses, Volume 19, Issue 11, November 2025.
ABSTRACT We estimated COVID‐19 vaccine effectiveness (VE) against PCR‐confirmed SARS‐CoV‐2 hospitalization in patients ≥ 60 years with severe acute respiratory infection, using a multicenter, test‐negative, case–control study across seven sites in six European countries between September 2024 and May 2025.
Madelyn Rojas‐Castro, Nuno Verdasca, Susana Monge, Laurane De Mot, Camino Trobajo‐Sanmartín, Róisín Duffy, Gergő Túri, Monika Kuliese, Ralf Duerrwald, Maria‐Louise Borg, Odette Popovici, Verónica Gomez, Zvjezdana Lovrić Makarić, Odile Launay, Diogo F. P. Marques, Francisco Pozo, Arne Witdouck, Iván Martínez‐Baz, Margaret Fitzgerald, Beatrix Oroszi, Ligita Jančorienė, Silke Buda, Ausra Dziugyte, Mihaela Lazăr, Ausenda Machado, Irena Tabain, Liem Binh Luong Nguyen, Eva Rivas Wagner, François Dufrasne, Jesús Castilla, Lisa Domegan, Viktória Velkey, Fausta Majauskaite, Carolin Hackmann, Nathalie Nicolay, Sabrina Bacci, Angela M. C. Rose, European Hospital Vaccine Effectiveness Group   +37 more
wiley   +1 more source

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut, Tuba Çiğdem Oğuzoğlu   +1 more
wiley   +1 more source

Analysis of BoDV-1 status, EEG resting-state alpha activity and pro-inflammatory cytokines in adults with and without major depressive disorder

Frontiers in Psychology
IntroductionIn severe cases, an infection with the Borna Disease Virus 1 (BoDV-1), the causative agent of Borna disease in horses, sheep, and other domestic mammals, was reported to be accompanied by cognitive dysfunctions, seizures, deep coma, or severe
Anna J. Torner, Bernhard T. Baune, Bernhard T. Baune, Bernhard T. Baune, Kristian Folta-Schoofs, Detlef E. Dietrich, Detlef E. Dietrich, Detlef E. Dietrich   +7 more
doaj   +1 more source

Clinical Improvisatory Music for Alzheimer's Disease Anxiety and Caregivers (CIMAC): Preliminary Behavioral and Network Modulation Findings from Ongoing Trials [PDF]

Alzheimers Dement
Abstract Background Approximately 40% of individuals with Alzheimer's disease (AD) experience anxiety (AD‐A), decreasing their quality of life and burdening caregivers. Anxiety medications can have negative side effects, prompting exploration of non‐pharmacological interventions like music.
Vidano K, Behn J, Takarabe C, Bonakdarpour B.   +3 more
europepmc   +2 more sources