Results 61 to 70 of about 4,924 (198)

Genomic and epigenomic insights into purkinje and granule cells in Alzheimer's disease‐related dementia using single‐nucleus multiome analysis

open access: yesAlzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Recent advances in single‐cell/nuclei multiome technology have enabled simultaneous profiling of gene expression and chromatin accessibility from the same nuclei, providing opportunities to interrogate the regulatory underpinnings responsible for Alzheimer's disease (AD) relevant transcriptomic and epigenomic features in a cell type‐
Feixiong Cheng   +4 more
wiley   +1 more source

Tödliches Borna-Virus: Zentrale Forschungsstelle entsteht

open access: yes, 2020
Das bayerische Gesundheitsministerium richtet in Regensburg (Bayern) eine zentrale Stelle zur Erforschung des sogenannten Borna-Virus ein. Laut Bayerischer Rundfunk soll das Projekt „Borna Focal Point Bayern“ voraussichtlich diesen Sommer ­starten und ...
aml
core  

Effect of antiviral substances on Borna Disease Virus in vitro [PDF]

open access: yes, 2007
Borna Disease is a severe, immunopathological disorder of the central nervous system, caused by infection with Borna Disease Virus. The main known naturally affected animal species are horses and sheep in endemic areas in central Europe. The detection of
Del Chicca, Francesca; https://orcid.org/
core   +1 more source

Musical Museum: An Interdisciplinary Approach to Integrative Life Enrichment for Individuals with Neurocognitive Disorders and their Care Partners

open access: yesAlzheimer's &Dementia, Volume 21, Issue S4, December 2025.
Abstract Background Social, emotional, and cognitive stimulation are protective factors that can slow neurocognitive disorder (NcD) progression, making them priorities for early and moderate dementia interventions. Live music programs with music appreciation content provide social‐emotional interaction, intellectual stimulation, and serve as social ...
Melanie Zhang   +4 more
wiley   +1 more source

Borna disease in naturally infected cattle

open access: yes, 1994
Based on the immunohistochemical demonstration of viral antigen and on the histological brain lesions, Borna disease was diagnosed in a cow and a bull which had suffered from a severe, subacute progressive disorder of the central nervous system.
Ehrensperger, F   +4 more
core   +1 more source

Analysis of BoDV-1 status, EEG resting-state alpha activity and pro-inflammatory cytokines in adults with and without major depressive disorder

open access: yesFrontiers in Psychology
IntroductionIn severe cases, an infection with the Borna Disease Virus 1 (BoDV-1), the causative agent of Borna disease in horses, sheep, and other domestic mammals, was reported to be accompanied by cognitive dysfunctions, seizures, deep coma, or severe
Anna J. Torner   +7 more
doaj   +1 more source

Clinical Improvisatory Music for Alzheimer's Disease Anxiety and Caregivers (CIMAC): Preliminary Behavioral and Network Modulation Findings from Ongoing Trials

open access: yesAlzheimer's &Dementia, Volume 21, Issue S4, December 2025.
Abstract Background Approximately 40% of individuals with Alzheimer's disease (AD) experience anxiety (AD‐A), decreasing their quality of life and burdening caregivers. Anxiety medications can have negative side effects, prompting exploration of non‐pharmacological interventions like music.
Kate Vidano   +3 more
wiley   +1 more source

MET‐FTD: Music‐based Empathy Training for Frontotemporal Dementia

open access: yesAlzheimer's &Dementia, Volume 21, Issue S4, December 2025.
Abstract Background Behavioral variant frontotemporal dementia (bvFTD) often presents with social cognition and behavior changes out of proportion to cognitive decline. BvFTD has the highest caregiver burden of any dementia, leading to significant marital problems not infrequently ending in divorce.
Kaitlin Seibert   +7 more
wiley   +1 more source

Experimental Infection: Pathogenesis of neurobehavioral Disease

open access: yes, 2002
Even though findings obtained from experimental Borna disease virus (BDV) infection of other species gave many insights into species-specific pathogenic processes, BDV infection of the rat is the most common model for studying the pathogenesis of Borna ...
Stitz, Lothar   +2 more
core   +1 more source

Infection of Borna disease virus in healthy animals in northern China

open access: yesAsian Pacific Journal of Tropical Medicine, 2018
Borna disease virus (BDV) is a non-segmented, single negative stranded RNA virus. It is highly neurotropic, but the infection is not cytopathic to the infected cells.
Ai-xia Zhai   +10 more
doaj   +1 more source

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