Results 101 to 110 of about 473,462 (215)
Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? [PDF]
, 2017 Human narcolepsy with cataplexy is a neurological disorder, which develops due to a deficiency in hypocretin producing neurons in the hypothalamus. There is a strong association with human leucocyte antigens HLA-DR2 and HLA-DQB1*0602.
Bassetti, Claudio L. +5 more
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Fatal Encephalitis Associated with Borna Disease Virus 1.
New England Journal of Medicine, 2018 Fatal Borna Disease Virus 1 Infection This report describes a fatal case of severe encephalitis due to Borna disease virus 1.
K. Korn +8 more
semanticscholar +1 more source
Antagonistic activity against innate immunity determines virulence in mammalian bornaviruses
npj VirusesVariegated squirrel bornavirus 1 (VSBV-1) is a lethal emerging disease that has been discovered in privately owned and zoo squirrels, but its pathogenicity as a zoonotic pathogen remains uncertain.
Akiko Makino +3 more
doaj +1 more source
Emerging roles of pathogens in Alzheimer disease [PDF]
, 2017 Chronic spirochetal infection can cause slowly progressive dementia, cortical atrophy and amyloid deposition in the atrophic form of general paresis.
Miklossy, Judith
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Reactive oxygen species and nitric oxide in viral diseases [PDF]
, 2018 Metabolites derived from superoxide (o2 •−) and nitric oxide (NO•) play an important role in antimicrobial and antitumoral defense, but may also harm the host.
Peterhans, Ernst
core
Frontiers in PsychologyIntroductionIn severe cases, an infection with the Borna Disease Virus 1 (BoDV-1), the causative agent of Borna disease in horses, sheep, and other domestic mammals, was reported to be accompanied by cognitive dysfunctions, seizures, deep coma, or severe
Anna J. Torner +7 more
doaj +1 more source
Emerging Microbes and InfectionsBorna disease virus 1 (BoDV-1) was just recently shown to cause predominantly fatal encephalitis in humans. Despite its rarity, bornavirus encephalitis (BVE) can be considered a model disease for encephalitic infections caused by neurotropic viruses and ...
Yannik Vollmuth +15 more
doaj +1 more source
Health care professionals at risk of infection with Borna disease virus – evidence from a large hospital in China (Chongqing) [PDF]
, 2015 Dan Zhu +13 more
core +1 more source
The structure of the mammalian bornavirus polymerase complex
Nature CommunicationsBorna disease virus 1 (BoDV-1) is a non-segmented RNA virus with one of the smallest known RNA virus genomes. BoDV-1 replicates in the nucleus of infected cells using a virally encoded polymerase complex composed of the large protein and phosphoprotein ...
Loïc Carrique +4 more
doaj +1 more source