Results 91 to 100 of about 5,371 (185)
Emerging Microbes and InfectionsBorna disease virus 1 (BoDV-1) was just recently shown to cause predominantly fatal encephalitis in humans. Despite its rarity, bornavirus encephalitis (BVE) can be considered a model disease for encephalitic infections caused by neurotropic viruses and ...
Yannik Vollmuth +15 more
doaj +1 more source
The microbial hypothesis : contributions of adenovirus infection and metabolic endotoxaemia to the pathogenesis of obesity [PDF]
, 2016 The global obesity epidemic, dubbed “globesity” by the World Health Organisation, is a pressing public health issue. The aetiology of obesity is multifactorial incorporating both genetic and environmental factors.
Pace, Nikolai Paul +2 more
core +4 more sources
Ethos, Volume 52, Issue 2, Page 308-323, June 2024.Abstract To explain cultural diversity, many theories refer to the social construction of reality. In this telling, we frame the world to make it meaningful. In my analysis of what people in Namibia and Germany know about “SARS‐Cov‐2” and “climate change,” I propose an anti‐constructivist alternative. Drawing on the work of the phenomenologist Bernhard
Michael Schnegg
wiley +1 more source
Xenotransplantation, Volume 31, Issue 3, May/June 2024.Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley +1 more source
miR-146a promotes Borna disease virus 1 replication through IRAK1/TRAF6/NF-κB signaling pathway
Virus Research, 2019 Borna disease virus 1 (BoDV-1) is a negative single-stranded RNA virus that is highly neurotropic. BoDV-1 infection can damage the central nervous system and cause inflammation. To survive in host cells, BoDV-1 must evade the host innate immune response.
Xiong, Zhang +9 more
openaire +2 more sources
FOXP3 deficiency, from the mechanisms of the disease to curative strategies
Immunological Reviews, Volume 322, Issue 1, Page 244-258, March 2024.Summary FOXP3 gene is a key transcription factor driving immune tolerance and its deficiency causes immune dysregulation, polyendocrinopathy, enteropathy X‐linked syndrome (IPEX), a prototypic primary immune regulatory disorder (PIRD) with defective regulatory T (Treg) cells.
Simon Borna, Eric Meffre, Rosa Bacchetta
wiley +1 more source
Potential Links between Hepadnavirus and Bornavirus Sequences in the Host Genome and Cancer
Frontiers in Microbiology, 2017 Various viruses leave their sequences in the host genomes during infection. Such events occur mainly in retrovirus infection but also sometimes in DNA and non-retroviral RNA virus infections.
Tomoyuki Honda
doaj +1 more source
Serological Surveillance and Risk Factor Analysis for Parrot Bornavirus in Taiwan
Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.Parrots are traded globally and pose a substantial risk for disease transmission involving parrot‐specific pathogens. Parrot bornavirus (PaBV) belongs to the Bornaviridae family and encompasses two clades: alphapsittaciforme (PaBV‐1 to ‐4, PaBV‐7, and ‐8) and betapsittaciforme (PaBV‐5 and PaBV‐6). These clades cause proventricular dilatation disease, a
Jing-Yuan Chen +4 more
wiley +1 more source
Are human Borna disease virus 1 infections zoonotic and fatal? [PDF]
The Lancet Infectious Diseases, 2020 Liv Bode +4 more
openaire +2 more sources
The Lancet Infectious DiseasesBorna disease, which is a severe encephalitis that primarily affects horses and sheep, has been recognised for over two centuries. Borna disease virus 1 (BoDV-1) has been identified as a cause of a predominantly fatal encephalitis in humans. Little scientific data exist regarding the virus' transmission, entry portal, and excretion routes.
Jungbäck, Nicola +10 more
openaire +3 more sources