Tumor Necrosis Factor-α Receptor 1 Mediates Borna Disease Virus 1-Induced Changes in Peroxisomal and Mitochondrial Dynamics in Neurons. [PDF]
Int J Mol SciBorna disease virus 1 (BoDV1) causes a persistent infection in the mammalian brain. Peroxisomes and mitochondria play essential roles in the cellular antiviral immune response, but the effect of BoDV1 infection on peroxisomal and mitochondrial dynamics and their respective antioxidant capacities is still not clear.
Osei D +3 more
europepmc +3 more sources
Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]
, 2019 Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda +7 more
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Mechanism of the Antiviral Action of 1-β-
Journal of Virology, 2005 ABSTRACT Borna disease virus (BDV) is a nonsegmented, negative-stranded RNA virus that causes neurological diseases in a variety of warm-blooded animal species. Recently, we showed that the nucleoside analog 1-β- d -arabinofuranosylcytosine (Ara-C) was a potent inhibitor of BDV.
Volmer, Romain +5 more
openaire +4 more sources
Viruses, 2023 Borna disease virus (BoDV-1) is a highly neurotropic RNA virus that causes neurobehavioral disturbances such as abnormal social activities and memory impairment.
Da Teng, Keiji Ueda, Tomoyuki Honda
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Characterization of the major nuclear localization signal of the Borna disease virus phosphoprotein [PDF]
, 1999 Borna disease virus (BDV) replicates and transcribes its negative-sense RNA genome in the nucleus. The BDV phosphoprotein (P) is localized in the nucleus of infected cells and cells transfected with P expression constructs.
Jehle, Christian +3 more
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Heat stress is a potent stimulus for enhancing rescue efficiency of recombinant Borna disease virus. [PDF]
, 2014 Recently developed vector systems based on Borna disease virus (BDV) hold promise as platforms for efficient and stable gene delivery to the central nervous system (CNS). However, because it currently takes several weeks to rescue recombinant BDV (rBDV),
Honda, Tomoyuki +3 more
core +1 more source
Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene) [PDF]
, 2009 Background Borna disease virus (BDV) is the type member of the Bornaviridae, a family of viruses that induce often fatal neurological diseases in horses, sheep and other animals, and have been proposed to have roles in certain psychiatric diseases of ...
Courtney E Garry, Robert F Garry
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Authentic Borna disease virus transcripts are spliced less efficiently than cDNA-derived viral RNAs [PDF]
, 2000 Borna disease virus (BDV) is a non-segmented, negative-strand RNA virus that replicates and transcribes its genome in the nucleus of infected cells. It uses the cellular splicing machinery to generate a set of alternatively spliced mRNAs from the 2.8 and
Jehle, Christian +4 more
core +2 more sources
iScience, 2022 Summary: Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin.
Florent Henri Marty +8 more
doaj +1 more source
Within host RNA virus persistence : mechanisms and consequences [PDF]
, 2017 RER is funded by the Wellcome Trust, UK (Grant 101788/Z/13/Z) and DEG by US National Institutes of Health (R01 NS038932).In a prototypical response to an acute viral infection it would be expected that the adaptive immune response would eliminate all ...
Griffin, Diane E., Randall, Richard E.
core +1 more source