Results 81 to 90 of about 5,371 (185)

Glutamate and lipid metabolic perturbation in the hippocampi of asymptomatic borna disease virus-infected horses. [PDF]

PLoS ONE, 2014
Borna disease virus (BDV) is a neurotropic, enveloped, non-segmented, negative-stranded RNA virus that infects a wide variety of vertebrate species from birds to humans across a broad global geographic distribution.
Liang Zhang, Yang Lei, Xia Liu, Xiao Wang, Zhao Liu, Dan Li, Peng Zheng, Lujun Zhang, Shigang Chen, Peng Xie   +9 more
doaj   +1 more source

Established and Emerging Roles of DEAD/H‐Box Helicases in Regulating Infection and Immunity

Immunological Reviews, Volume 329, Issue 1, January 2025.
ABSTRACT The sensing of nucleic acids by DEAD/H‐box helicases, specifically retinoic acid‐inducible gene I (RIG‐I) and melanoma differentiation‐associated protein 5 (MDA5), plays a critical role in inducing antiviral immunity following infection. However, this DEAD/H‐box helicase family includes many additional proteins whose immune functions have not ...
Michael Parthun, Matthew E. Long, Emily A. Hemann   +2 more
wiley   +1 more source

RNA splicing at human immunodeficiency virus type 1 3 ' splice site A2 is regulated by binding of hnRNP A/B proteins to an exonic splicing silencer element [PDF]

, 2001
The synthesis of human immunodeficiency virus type 1 (HIV-1) mRNAs is a complex process by which more than 30 different mRNA species are produced by alternative splicing of a single primary RNA transcript.
Bilodeau, P. S., Domsic, J. K., Krainer, A. R., Mayeda, A., Stoltzfus, C. M.   +4 more
core   +2 more sources

Activation of ERK/CREB/BDNF pathway involved in abnormal behavior of neonatally Borna virus-infected rats

Neuropsychiatric Disease and Treatment, 2018
Chenmeng Li,1–3,* Xiaoyan Xu,2–4,* Xiong Zhang,2–4,* Ke Cheng,2,3,* Yujie Guo,1–3 Jie Jie,1–3 Hua Guo,1–3 Yong He,1–3 Chanjuan Zhou,2,3 Siwen Gui,2,3 Xiaogang Zhong,2,3 Haiyang Wang,2–4 Peng Xie1–4 ...
Li C, Xu X, Zhang X, Cheng K, Guo Y, Jie J, Guo H, He Y, Zhou C, Gui S, Zhong X, Wang H, Xie P   +12 more
doaj  

Toxoplasma gondii Infection of BALB/c Mice Perturbs Host Neurochemistry

Parasite Immunology, Volume 46, Issue 11, November 2024.
ABSTRACT Toxoplasma gondii infection has been associated with psychoneurological disease in humans and behavioural changes in rodents. However, the mechanisms accounting for this have not been fully described and in some cases could be argued to reflect the severe neuropathology that some mice suffer during infection.
Aisha A. Abdelati Abdelsalam, Stuart Woods, Selina Henriquez, Lucy Curran, Gareth Westrop, Craig W. Roberts   +5 more
wiley   +1 more source

Word recognition memory and serum levels of Borna disease virus specific circulating immune complexes in obsessive–compulsive disorder

BMC Psychiatry, 2022
Background Borna disease virus 1 (BoDV-1) is a non-segmented, negative-strand RNA virus that persistently infects mammals including humans. BoDV-1 worldwide occurring strains display highly conserved genomes with overlapping genetic signatures between ...
Yuanyuan Zhang, A Alwin Prem Anand, Liv Bode, Hanns Ludwig, Hinderk M. Emrich, Detlef E. Dietrich   +5 more
doaj   +1 more source

The nonstructural protein NSs of Schmallenberg virus is targeted to the nucleolus and induces nucleolar disorganization [PDF]

, 2016
Schmallenberg virus (SBV) was discovered in Germany in late 2011 and then spread rapidly to many European countries. SBV is an orthobunyavirus that causes abortion and congenital abnormalities in ruminants.
Breard, Emmanuel, Caignard, Grégory, Cochet, Marielle, Coulpier, Muriel, Fablet, Aurore, Gouzil, Julie, Kundlacz, Cindy, Lara, Estelle, Palmarini, Massimo, Sailleau, Corinne, Varela, Mariana, Viarouge, Cyril, Vitour, Damien, Zientara, Stéphan   +13 more
core   +2 more sources

Infection burden, periodontal pathogens, and their interactive association with incident all‐cause and Alzheimer's disease dementia in a large national survey

Alzheimer's &Dementia, Volume 20, Issue 9, Page 6468-6485, September 2024.
Abstract INTRODUCTION Relationships and interplay of an infection burden (IB) and periodontal pathogens or periodontal disease (Pd) markers with Alzheimer's disease (AD) and all‐cause dementia among US adults were examined. METHODS Less than or equal to 2997 participants from the National Health and Nutrition Survey III were linked to CMS‐Medicare [≥45
May A. Beydoun, Hind A. Beydoun, Dawson W. Hedges, Lance D. Erickson, Shawn D. Gale, Jordan Weiss, Ziad W. El‐Hajj, Michele K. Evans, Alan B. Zonderman   +8 more
wiley   +1 more source

Humane Infektionen mit dem Borna Disease Virus (BoDV-1)

, 2018
Untersuchungen des Friedrich-Loeffler-Instituts (FLI) in Zusammenarbeit u.a. mit den Universitäts­kliniken in Regensburg, München und Leipzig identifizierten erstmals das klassische Bornavirus (Borna disease virus 1, BoDV-1; Spezies Mammalian 1 Bornavirus) als wahrscheinlichen Auslöser von schweren Entzündungen des Gehirns (Enzephalitis) beim Menschen.
openaire   +2 more sources

Tumour or haemorrhage?: Differential diagnosis of an unknown mass within the brain of a budgerigar (Melopsittacus undulatus) using a novel imaging pipeline

Veterinary Record Case Reports, Volume 12, Issue 3, September 2024.
Abstract We report on a previously healthy zoo specimen of an adult budgerigar (Melopsittacus undulatus, obtained with permission from Southwick's Zoo) found deceased in its enclosure. To assess cause of death and ensure the absence of an infectious neoplasia, we used an integrated multiscale brain‐imaging workflow, previously only used on mammals. The
Tatiana Vasquez, Paul M. Gignac, Peter Brewer, Maria Eugenia Leone Gold   +3 more
wiley   +1 more source