Results 91 to 100 of about 3,395,639 (199)

Boron-Containing MOF Nanoparticles with Stable Metabolism in U87-MG Cells Combining Microdosimetry To Evaluate Relative Biological Effectiveness of Boron Neutron Capture Therapy

Accurate prediction of the relative biological effectiveness (RBE) of boron neutron capture therapy (BNCT) is challenging. The therapy is different from other radiotherapy; the dynamic distribution of boron-containing compounds in tumor cells affects the
Qiuyang Liu (7771766), Ziteng Chen (8586780), Gengmei Xing (468039), Linwen Lv (14236786), Zhijie Wang (283745), Jingru Yang (2626306), Weihua Zhang (44940), Jiacheng Li (826240), Tong Liu (107783), Ya-nan Chang (8586783), Jianfei Tong (16002107), Tianjiao Liang (10739105), Hongyu Tang (7508135), Kui Chen (157443), Linbo Zhu (17787633), Mengyao Li (2634310), Runhong Lei (4776399), Zizhu Zhang (6052052), Meiru Mao (8586777), Xianwei Luo (13915305), Juan Li (146180), Jiaxin Zhang (1836484), Ruyu Yan (785247), Hui Yuan (402180)   +23 more
core   +1 more source

Optimization of the geometry and composition of a neutron system for treatment by Boron Neutron Capture Therapy

Iranian South Medical Journal, 2015
Background: In the field of the treatment by Boron Neutron Capture Therapy (BNCT), an optimized neutron system was proposed. This study (simulation) was conducted to optimize the geometry and composition of neutron system and increase the epithermal ...
Rohollah Gheisari, Mohmmadmehdi Firoozabadi, Habib Mohammadi   +2 more
doaj  

An optimal design of beam shaping assembly for BNCT based on 7Li(p,n)7Be of 3.5 MeV proton accelerator

Nukleonika
Accelerator-based neutron sources offer an attractive alternative to nuclear reactors for boron neutron capture therapy (BNCT) due to their unique advantages, including low cost, safety, and the feasibility of hospital installation.
Huang Hong, Yan Yucheng, Fu Tao
doaj   +1 more source

Boron-Containing Mesoporous Silica Nanoparticles with Effective Delivery and Targeting of Liver Cancer Cells for Boron Neutron Capture Therapy

Nanocarriers have been researched comprehensively for the development of novel boron-containing agents in boron neutron capture therapy (BNCT). We designed and synthesized a multifunctional mesoporous silica nanoparticle (MSN)-based boron-containing ...
Fan Hu (277859), Qiuyang Liu (7771766), Ziteng Chen (8586780), Gengmei Xing (468039), Lingna Zheng (1645990), Linwen Lv (14236786), Zhijie Wang (283745), Jingru Yang (2626306), Mingxin Yang (9455424), Weixian Luo (18466308), Ya-nan Chang (8586783), Hao Li (31608), Hongyu Tang (7508135), Ranran Chen (3308463), Wenxi Su (18466311), Kui Chen (157443), Mengyao Li (2634310), Haoyang Hao (11177971), Haojun Liang (105234), Meng Wang (124646), Xuesong Feng (754835), Junhui Zhang (493124), Juan Li (146180), Ruyu Yan (785247)   +23 more
core   +1 more source

Proposal and Analysis of "Ternary" Model of Sensitization for Proton Therapy

Zhongguo yiliao qixie zazhi
In order to improve the biological effect of proton therapy, the authors first propose a new method of boron-based proton-enhanced radiotherapy in a " ternary " radiotherapy mode, based on the existing sensitizing effect of proton radiotherapy: i.e ...
Xiaowa WANG, Xufei WANG, Ning DU, Lan WANG   +3 more
doaj   +1 more source

Current status of dosimetry at the boron neutron capture therapy facility at Studsvik, Sweden

, 2002
The beam was successfully characterized in air and in phantom using various radiation dosimeter:,. The determination of the thermal neutron and photon components of the mixed beam in phantom can be determined with acceptable uncertainties, while the ...
Giusti, V, Ceberg, Crister,, Persson, Bertil R,, Munck af Rosenschöld, Per,, Andreoiu, Corina, H-Stenstam, B, Salford, Leif,, Capala, J, Lund University., Skold, K   +9 more
core  

A bifunctional carborane-quinazoline combines tumor growth inhibition and boron delivery for boron neutron capture therapy in melanoma and non-small cell lung cancer models

Frontiers in Chemical Biology
BackgroundBoron neutron capture therapy (BNCT) is a binary therapeutic modality based on the nuclear reaction between boron-10 (10B) and low-energy neutrons, generating high-linear-energy-transfer (LET) α-particles (4He) and recoiling lithium-7 (7Li ...
María Alejandra Dagrosa, María Alejandra Dagrosa, María Alejandra Dagrosa, Marina Carpano, Antonella Pastini, Antonella Pastini, Estanislao Pavlik, Andrés Bechis, Andrés Bechis, María Silvina Olivera, Pablo Vallecorsa, Belén Dávila, Belén Dávila, Luciano Parodi, Esther Yardena Salem, María Sol Espain, María Sol Espain, Agustina Mariana Portu, Agustina Mariana Portu, Laura Todaro, Laura Todaro, Alejandro Urtreger, Alejandro Urtreger, Pablo Menendez, Hugo Cerecetto, Hugo Cerecetto, Hugo Cerecetto, Marcos Couto, Marcos Couto   +28 more
doaj   +1 more source

Advances in the autoradiography technique for Boron-10 quantification in bone

, 2016
Boron neutron capture therapy research is influenced by the latest advances in science and technology, which promote the increase of clinical scenarios that can be treated with this chemically targeted form of radiotherapy. One of those is osteosarcoma,
, M. S. Olivera, ALTIERI, SAVERIO, BORTOLUSSI, SILVA, S. J. González, A. M. Portu, , I. Postuma, G. Saint Martin, L. Provenzano   +7 more
core  

Analysis of boron neutron capture reaction sensitivity using Monte Carlo simulation and proposal of a new dosimetry index in boron neutron capture therapy

Analysis of boron neutron capture reaction sensitivity using Monte Carlo simulation and proposal of a new dosimetry index in boron neutron capture therapy
Boron neutron capture therapy is a cellular-scale heavy-particle therapy. The factor determining the biological effects in the boron neutron capture reaction (BNCR) is the value of αboron ⁠, which is the alpha component in the Linear Quadratic (LQ) model.
openaire   +1 more source

Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model

, 2008
Background: Boron neutron capture therapy usually relies on soluble, rather than particulate, boron compounds. This study evaluated the use of a novel boron nanoparticle for boron neutron capture therapy.
Sutmutter, Marjolein, Sørensen, Palle G., Hansen, Thomas, Bjørnholm, Thomas, Gundersen, Hans Jørgen, Petersen, Mikkel Steen, Petersen, Charlotte Christie, Agger, Ralf, Huiskamp, Rene, Hokland, Marianne, Jensen, Martin Roland, Mortensen, Michael Wrang   +11 more
core   +1 more source