Results 111 to 120 of about 12,901 (257)

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Asymmetric Copper-Catalyzed Synthesis of α-Amino Boronate Esters from N-tert-Butanesulfinyl Aldimines

, 2016
Asymmetric Copper-Catalyzed Synthesis of α-Amino Boronate Esters from N-tert-Butanesulfinyl ...
Jonathan A. Ellman (610362), Melissa A. Beenen (2436487), Chihui An (1679446)   +2 more
core   +2 more sources

Polycarbonate Vitrimers and Dynamic Co‐Networks From Epoxide/Carbon Dioxide Copolymerization

Macromolecular Rapid Communications, EarlyView.
This work demonstrates how CO2‐derived poly(propylene carbonate) and poly(cyclohexene carbonate) backbones influence vitrimer thermo‐mechanical behavior. By tuning backbone composition, epoxide crosslinker chemistry and blend ratios, the crosslinked materials span a wide property window, from highly extensible to stiff, glassy networks, establishing an
Satej S. Joshi, Sophia Aracri, Mark D. Foster, James M. Eagan   +3 more
wiley   +1 more source

Cumulative release of insulin from boronate-AVTs in the absence of glucose trigger.

, 2012
Cumulative release of insulin from boronate-AVTs in the absence of glucose trigger.
Eric A. Tanifum (123168), Claudio N. Cavasotto (187746), Ananth Annapragada (123214), Indrani Dasgupta (123170), Sharangdhar S. Phatak (187743), Mostafa Analoui (187748), Mayank Srivastava (123173)   +6 more
core   +1 more source

A ROS and pH dual - responsive hydrogel-nanoparticle system restores intervertebral disc and alleviates related pain by modulating senescence and panoptosis of nucleus pulposus cells

Materials Today Bio
Intervertebral disc degeneration (IVDD) is a common cause of low back pain (LBP). We developed a dual-responsive hydrogel-nanoparticle system (PCL5 system), incorporating PLGA-mPEG nanoparticles, boronate-modified dextran (ODex-ABA), catechol ...
Wenjie Zhong, Lingcong Xu, Niezhenghao He, Wenao Liao, Caiyuan Liu, Ke Xu, Xing Chen, Wei Zhang, Jiang Hu, Xiaojing Wu, Haowen Cui   +10 more
doaj   +1 more source

Coupled Environmental Effects in Competitive Inhibition of Dynamic Hydrazone Hydrogels

Macromolecular Rapid Communications, EarlyView.
Environment Alters Competitive Inhibition of Crosslinks. Ion concentration, pH, and buffer composition govern exchange kinetics and network stability in dynamic benzyl‐hydrazone hydrogels. These factors are particularly important when utilizing small‐molecule competitors for enhanced control over gel mechanics, underscoring the need to control the ...
Sirilak Mekcham, Alexander D. Claiborne, Megan S. Rothenberg, Owen A. Lee, Elizabeth Thompson, Megan R. Hill   +5 more
wiley   +1 more source

A Highly Efficient Fluorescent Turn-Off Nanosensor for Quantitative Detection of Teicoplanin Antibiotic from Humans, Food, and Water Based on the Electron Transfer between Imprinted Quantum Dots and the Five-Membered Cyclic Boronate Esters

Molecules
Teicoplanin has been banned in the veterinary field due to the drug resistance of antibiotics. However, teicoplanin residue from the antibiotic abuse of humans and animals poses a threat to people’s health.
Yansong Zhang, Daojin Li, Xiping Tian
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source