Results 51 to 60 of about 12,901 (257)

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Borylated 5-Membered Ring Iminosugars: Synthesis and Biological Evaluation for Glycosidase Inhibition and Anticancer Properties for Application in Boron Neutron Capture Therapy (BNCT)—Part 2

Pharmaceuticals
Background: The synthesis and biological investigation of pyrrolidine (L-gulo) iminosugars bearing an organic boron pharmacophore in ortho and meta positions of an N-benzyl group is reported.
Kate Prichard, Kosuke Yoshimura, Suzuka Yamamoto, Atsumi Taguchi, Barbara Bartholomew, Jayne Gilbert, Jennette Sakoff, Robert Nash, Atsushi Kato, Michela Simone   +9 more
doaj   +1 more source

Novel Silsesquioxane-Derived Boronate Esters—Synthesis and Thermal Properties

Molecules, 2021
The functionalization of mono- and octahydrospherosilicate with vinylboranes and allylboranes via hydrosilylation reaction in the presence of a Karstedt’s platinum (0) catalyst is presented.
Miłosz Frydrych, Daria Pakuła, Bogna Sztorch, Dariusz Brząkalski, Robert E. Przekop, Bogdan Marciniec   +5 more
doaj   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Boronate Based Metal-Free Platform for Diphosphate-Specific Molecular Recognitions

, 2016
A reversible boronate–diol interaction provides a versatile synthetic platform for molecular recognitions whose binding specificity can be molecularly tailored.
Daisuke Iizuka (455515), Yuji Miyahara (316939), Mai Sanjoh (1677025), Akira Matsumoto (408450)   +3 more
core   +1 more source

Aromatic Pummerer‐Promoted Stereospecific Cross‐Coupling of Thiazoles With Boronic Esters

Angewandte Chemie, EarlyView.
A lithiation–borylation–aromatic Pummerer (LiBAP) strategy enables stereospecific, C5‐selective C(sp2)–C(sp3) cross‐coupling of thiazoles with boronic esters. By using exocyclic sulfoxide activation to overcome the low nucleophilicity that frustrates SEAr‐type coupling, the method delivers enantioenriched alkylated thiazoles bearing a versatile C2 ...
Mark John P. Mandigma, Julien Lefranc, Louise Eagling, Jasper L. Tyler, Varinder K. Aggarwal   +4 more
wiley   +2 more sources

Investigation of the Interaction between Ferroceneboronic Acid and Sugars and Its Application in Probing of Enzyme Activity

International Journal of Electrochemical Science, 2013
Sugars play important roles in many biological processes, such as nutrition, metabolism, cell structure formation, and immunological protection. Phenylboronic acid (PBA) derivatives have been widely used as recognition molecules for sugars based on the ...
Xiaojin Wang, Lijiao Zhang, Fengyun Gu, Xiaojie Zhang, Ning Xia   +4 more
doaj   +1 more source

Non inflammatory boronate based glucose-responsive insulin delivery systems. [PDF]

PLoS ONE, 2012
Boronic acids, known to bind diols, were screened to identify non-inflammatory cross-linkers for the preparation of glucose sensitive and insulin releasing agglomerates of liposomes (Agglomerated Vesicle Technology-AVT).
Indrani Dasgupta, Eric A Tanifum, Mayank Srivastava, Sharangdhar S Phatak, Claudio N Cavasotto, Mostafa Analoui, Ananth Annapragada   +6 more
doaj   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

Advanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang, Xin Li, Ying Xiong, Xin Wang, Ying‐Wei Yang   +4 more
wiley   +1 more source

Study of Porous Materials Incorporating Boronate Esters

, 2011
COF-18Å is one type of Covalent Organic Framework (COF) that incorporates self-assembling covalent bonded boronate esters as secondary building units to form a porous material.
Sapp, Kevin Scott
core   +1 more source