Results 31 to 40 of about 30,156 (257)

Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters [PDF]

, 2011
The first enantioselective Pd-catalyzed construction of all-carbon quaternary stereocenters via 1,4-addition of arylboronic acids to β-substituted cyclic enones is reported. Reaction of a wide range of arylboronic acids and cyclic enones using a catalyst
Gatti, Michele, Holder, Jeffrey C., Kikushima, Kotaro, Stoltz, Brian M.   +3 more
core   +2 more sources

Spectroscopic studies of the Chan–Lam amination: a mechanism-inspired solution to boronic ester reactivity [PDF]

, 2017
We report an investigation of the Chan–Lam amination reaction. A combination of spectroscopy, computational modeling, and crystallography has identified the structures of key intermediates and allowed a complete mechanistic description to be presented ...
Isidro-Llobet, Albert, Miras, Haralampos N., Sproules, Stephen, Vantourout, Julien C., Watson, Allan J.B.   +4 more
core   +5 more sources

Boronic Acid-Based Electrochemical Sensors for Detection of Biomolecules

International Journal of Electrochemical Science, 2013
Boronic acids can form reversible covalent bonds with 1, 2- or 1, 3-diols to generate five or six-membered cyclic complexes. Thus, boronic acid functionalized compounds and materials have attracted much attention in both chemistry and biology as the ...
Lin Liu, Ning Xia, Yun Xing, Dehua Deng
doaj   +1 more source

Recent developments in the Suzuki-Miyaura reaction: 2010-2014 [PDF]

, 2015
The Suzuki-Miyaura reaction (SMR), involving the coupling of an organoboron reagent and an organic halide or pseudo-halide in the presence of a palladium or nickel catalyst and a base, has arguably become one of most utilized tools for the construction ...
Maluenda, Irene, Navarro, Oscar
core   +2 more sources

Rapid iododeboronation with and without gold catalysis: application to radiolabelling of arenes [PDF]

, 2017
Radiopharmaceuticals incorporating radioactive iodine in combination with SPECT imaging play a key role in nuclear medicine, with applications in drug development and disease diagnosis.
Fletcher, Conor, Lee, Ai-Lan, O'Rourke, Kerry M., Pimlott, Sally L., Sutherland, Andrew, Webster, Stacey   +5 more
core   +2 more sources

One-pot synthesis of four-coordinate boron(III) complexes by the ligand-promoted organic group migration between boronic acids

Scientific Reports, 2017
Multidisciplinary applications of four-coordinate boron(III) complexes make them very attractive and challenging research field in chemistry, biology and material sciences.
Venkata S. Sadu, Hye-Rin Bin, Do-Min Lee, Kee-In Lee   +3 more
doaj   +1 more source

Electrophilic Trifluoromethylselenolation of Boronic Acids

Molecules, 2017
Trifluoromethylselenylated compounds are emergent compounds with interesting physicochemical properties that still suffer from a lack of efficient synthetic methods.
Clément Ghiazza, Anis Tlili, Thierry Billard   +2 more
doaj   +1 more source

Asymmetric Synthesis of 1-Heteroaryl-1-arylalkyl Tertiary Alcohols and 1-Pyridyl-1-arylethanes by Lithiation-Borylation Methodology [PDF]

, 2013
The synthesis of highly enantioenriched alpha-heterocyclic tertiary alcohols has been achieved via lithiation-borylation of a configurationally stable lithiated carbamate and heterocyclic pinacol boronic esters followed by oxidation. Protodeboronation of
Aggarwal V. K., Biradar D. B., Biradar D. B., Carstens A., Charlotte G. Watson, Chen C.-A., Cozzi P. G., Dosa P. I., García C., García C., García C., Garg D. C., Greene M. A., Hatano M., Hatano M., Hatano M., Hoppe D., Hu Q., Kanai M., Luderer M. R., Madduri A. V. R., Madduri A. V. R., Maity P., Matsunaga N., Messaoudi S., Moree W. J., Nave S., Ou L., Pathak T. P., Ramón D. J., Ramón D. J., Shi S.-L, Shibasaki M., Song S., Starck J. P., Stymiest J. L., Taylor B. L. H., Varinder K. Aggarwal, Wada R., Weber B., Yus M., Yus M.   +41 more
core   +3 more sources

Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]

, 2007
Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L.,, Jagt, Richard B.C.,, Minnaard, Adriaan J.,, Schudde, Ebe P.,, Toullec, Patrick Y.,, Vries, Johannes G. de,   +5 more
core   +1 more source

Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical research due to their exceptional oxophilicity, low toxicity, and unique structure. They are known as potent enzyme inhibitors, cancer therapy capture agents, and can
Mothana K. Al-Omari, Mai Elaarag, Raed M. Al-Zoubi, Ahmad R. Al-Qudimat, Ayman A. Zarour, Enas A. Al-Hurani, Zainab E. Fares, Leena M. Alkharraz, Mohanad Shkoor, Abdulilah D. Bani-Yaseen, Omar M. Aboumarzouk, Aksam Yassin, Abdulla A. Al-Ansari   +12 more
doaj   +1 more source