Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis [PDF]
Scientific Reports, 2021 BB0405 is a surface exposed Borrelia burgdorferi protein and its vaccination protected mice against B. burgdorferi infection. As BB0405 is highly conserved across different B.
M. J. Klouwens +8 more
doaj +4 more sources
Serological evidence of possible Borrelia afzelii lyme disease in Greece [PDF]
New Microbes and New Infections, 2022 Suggestions that Lyme disease exists in Greece remain controversial and no study to date has definitively identified the presence of a Borrelia species that infects humans.
I. Karageorgou +5 more
doaj +3 more sources
Identification of Tick Ixodes ricinus Midgut Genes Differentially Expressed During the Transmission of Borrelia afzelii Spirochetes Using a Transcriptomic Approach [PDF]
Frontiers in Immunology, 2021 Lyme borreliosis is an emerging tick-borne disease caused by spirochetes Borrelia burgdorferi sensu lato. In Europe, Lyme borreliosis is predominantly caused by Borrelia afzelii and transmitted by Ixodes ricinus.
Sazzad Mahmood +9 more
doaj +3 more sources
Tick-to-host transmission differs between Borrelia afzelii strains [PDF]
Microbiology Spectrum, 2023 Many vector-borne pathogens establish multiple-strain infections in the vertebrate host and the arthropod vector. Multiple-strain infections in the host influence strain acquisition by naive vectors.
Dolores Genné +3 more
doaj +5 more sources
The genetic diversity of Borrelia afzelii is not maintained by the diversity of the rodent hosts [PDF]
Parasites & Vectors, 2018 Background Small mammals are essential in the enzootic cycle of many tick-borne pathogens (TBP). To understand their contribution to the genetic diversity of Borrelia afzelii, the most prevalent TBP in questing Ixodes ricinus, we compared the genetic ...
Claudia E. Coipan +4 more
doaj +5 more sources
Aseptic Meningitis Linked to Borrelia afzelii Seroconversion in Northeastern Greece: An Emerging Infectious Disease Contested in the Region [PDF]
Tropical Medicine and Infectious DiseaseBorreliosis (Lyme disease) is a zoonosis, mediated to humans and small mammals through specific vectors (ticks), with increasing global incidence. It is associated with a variety of clinical manifestations and can, if not promptly recognized and left ...
Dimitrios Kouroupis +10 more
doaj +2 more sources
A Novel High Discriminatory Protocol for the Detection of Borrelia afzelii, Borrelia burgdorferi Sensu Stricto and Borrelia garinii in Ticks [PDF]
Pathogens, 2022 Bacteria of the Borrelia burgdorferi sensu lato complex are the causative agents of Lyme borreliosis (LB). Even if the conventional diagnosis of LB does not rely on the species itself, an accurate species identification within the complex will provide a ...
Giulia Chiappa +11 more
doaj +2 more sources
The Emerging Role of Microbial Biofilm in Lyme Neuroborreliosis [PDF]
Frontiers in Neurology, 2018 Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia, respectively.
Enea Gino Di Domenico +10 more
doaj +4 more sources
Microbiota perturbation by anti-microbiota vaccine reduces the colonization of Borrelia afzelii in Ixodes ricinus [PDF]
Microbiome, 2023 Background Ticks can transmit a broad variety of pathogens of medical importance, including Borrelia afzelii, the causative agent of Lyme borreliosis in Europe.
Alejandra Wu-Chuang +13 more
doaj +2 more sources
A metalloprotease secreted by an environmentally acquired gut bacterium hinders Borrelia afzelii colonization in Ixodes ricinus [PDF]
Frontiers in Cellular and Infection MicrobiologyAlthough the importance of the microbiome in the context of tick biology and vector competence has recently come into a broader research focus, the field is still in its infancy and the complex ecological interactions between the tick residential ...
Adnan Hodžić +11 more
doaj +2 more sources