Optimising Transformation Efficiency in Borrelia: Unravelling the Role of the Restriction-Modification System of Borrelia afzelii and Borrelia garinii. [PDF]
Borrelia spp. are transmitted to humans by the bite of an infected tick. In Europe, Borrelia afzelii and Borrelia garinii are the main causative agents of Lyme borreliosis, one of the most prevalent tick-borne diseases in the northern hemisphere. In bacteria such as Borrelia spp., a restriction-modification system (RMS) protects against the harmful ...
Ruivo M +8 more
europepmc +3 more sources
Complete Genome Sequencing of Borrelia valaisiana and Borrelia afzelii Isolated from Ixodes persulcatus Ticks in Western Siberia [PDF]
ABSTRACT Lyme disease, caused by bacteria of the Borrelia burgdorferi sensu lato complex, is the most frequent tick-borne infection in Eurasia. Here, we report the complete genome sequence of the Borrelia valaisiana Tom 4006 and Borrelia afzelii ...
Alexander Kurilshikov +6 more
openalex +3 more sources
The Heterogeneity, Distribution, and Environmental Associations of Borrelia burgdorferi Sensu Lato, the Agent of Lyme Borreliosis, in Scotland [PDF]
Genospecies controls were obtained from the laboratory of Dr. Muriel Cornet at the Institut Pasteur, Paris. We thank Bob Furness for collecting ticks from passerine birds, Steph Vollmer for processing the samples from one site, E. Packer, A.
Bowman, Alan S +3 more
core +8 more sources
Lyme disease is a tick-borne infectious disease caused by the Borrelia burgdorferi sensu lato complex. However, the distribution of Borrelia genospecies and the tissue detection rate of Borrelia in wild rodents have rarely been investigated.
Choon Mee Kim +4 more
doaj +1 more source
Complement has been considered as an important factor impacting the host–pathogen association of spirochetes belonging to the Borrelia burgdorferi sensu lato complex, and may play a role in the spirochete’s ecology.
Valerie Sürth +4 more
doaj +1 more source
Borrelia afzelii-associated seronegative Lyme neuroborreliosis in an immunocompromised patient [PDF]
This case highlights the diagnostic complexity of Lyme neuroborreliosis (LNB) in immunosuppressed patients. A 62-year-old man with a history of follicular lymphoma, previously treated with R-Bendamustine and currently rituximab, presented with generalized symptoms and systemic inflammation.
Finn Gustafsson +6 more
openalex +3 more sources
Early cytokine release in response to live Borrelia burgdorferi Sensu Lato Spirochetes is largely complement independent. [PDF]
AIM: Here we investigated the role of complement activation in phagocytosis and the release of cytokines and chemokines in response to two clinical isolates: Borrelia afzelii K78, which is resistant to complement-mediated lysis, and Borrelia garinii LU59,
Kerstin Sandholm +7 more
doaj +1 more source
Genetic Markers for Detecting the DNA of Pathogenic Borrelia
The aim of the study was to analyze the genetic markers of Lyme disease pathogens, which can be used to specifically indicate maximum number of their strains and isolates. Materials and methods.
N. I. Khammadov, A. I. Khamidullina
doaj +1 more source
Ability to cause erythema migrans differs between Borrelia burgdorferi sensu lato isolates [PDF]
Background: Lyme borreliosis is a tick-borne disease caused by Borrelia burgdorferi sensu lato. The variety of characteristic and non-specific clinical manifestations is partially explained by its genetic diversity.
Hengeveld, P. (Paul) +5 more
core +9 more sources
Genospecies Diversity of Borrelia in Ixodes Ticks of the West Siberia
Objective: to determine genospecies composition of Borrelia in the ixodid ticks of various species in natural foci of Ixodes tick-borne borreliosis (ITB) in the South of Western Siberia. Materials and methods.
S. A. Rudakova +5 more
doaj +1 more source

