Bacterial Outer Membrane Vesicles: From Physics to Clinical
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou+7 more
wiley +1 more source
Simultaneous detection and genotyping of three genomic groups of Borrelia burgdorferi sensu lato in Dutch Ixodes ricinus ticks by characterization of the amplified intergenic spacer region between 5S and 23S rRNA genes [PDF]
We developed a rapid and reliable method for the identification Borrelia burgdorferi sensu lato species in ticks. We used the DNA sequence polymorphism of the spacer region between 5S and 23S rRNA genes, which has been shown to be able to discriminate between eight genomic groups of B. burgdorferi sensu lato (D. Postic, M. Assous, P. A. D. Grimont, and
M. J. C. H. Molkenboer+4 more
openaire +2 more sources
Protective immunity elicited by recombinant bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine. [PDF]
The current vaccine against tuberculosis, Mycobacterium bovis strain bacille Calmette-Guerin (BCG), offers potential advantages as a live, innately immunogenic vaccine vehicle for the expression and delivery of protective recombinant antigens (Stover, C ...
Bansal, GP+9 more
core
Impact of Iron Deficiency on the Growth and Bioelectrical Profile of Different Gut Bacteria
This study explores how iron deficiency (ID) affects Escherichia coli (E. coli) and Limosilactobacillus reuteri (L. reuteri) under laboratory conditions induced by the iron chelator 2,2'‐Bipyridyl (BP). L. reuteri showed no significant changes, whereas E.
Elisa Quarta+14 more
wiley +1 more source
Correlation property of length sequences based on global structure of complete genome [PDF]
This paper considers three kinds of length sequences of the complete genome. Detrended fluctuation analysis, spectral analysis, and the mean distance spanned within time $L$ are used to discuss the correlation property of these sequences.
A. Arneodo+36 more
core +4 more sources
Brucella canis in two juvenile labrador retriever littermates with no known travel history
Abstract Two labrador retriever littermates presented separately to investigate chronic lethargy and shifting lameness. In both cases, clinical examination revealed a multi‐limb lameness. Neither the patients nor their dam or sire had a travel history outside the UK.
Amy Lord+5 more
wiley +1 more source
Land Use Change and Infectious Disease Emergence
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli+6 more
wiley +1 more source
An Enzyme-Linked Immunosorbent Spot Assay Measuring Borrelia burgdorferi B31-Specific Interferon Gamma-Secreting T Cells Cannot Discriminate Active Lyme Neuroborreliosis from Past Lyme Borreliosis: a Prospective Study in the Netherlands. [PDF]
Two-tier serology testing is most frequently used for the diagnosis of Lyme borreliosis (LB); however, a positive result is no proof of active disease. To establish a diagnosis of active LB, better diagnostics are needed. Tests investigating the cellular
Bossink, A W J+11 more
core +1 more source
Sufficient reproduction numbers to prevent recurrent epidemics
Abstract Current practice in the design and evaluation of control measures in disease ecology and epidemiology, including vaccination, is largely based on reproduction numbers (RNs), which represent prognostic indices of long‐term disease transmission, both in naïve populations (basic RN) and in the presence of prior exposure or infection containment ...
Lorenzo Mari+3 more
wiley +1 more source
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey+5 more
wiley +1 more source