Results 91 to 100 of about 38,526 (184)

PSMD12 Overexpression Promotes Lung Adenocarcinoma Progression via Ubiquitin–Proteasome Pathway Dysregulation

open access: yesCancer Science, Volume 117, Issue 3, Page 644-656, March 2026.
PSMD12, located on the frequently amplified 17q region in LUAD, is upregulated in tumors and associated with poor prognosis and advanced stage. Functional studies revealed that PSMD12 promotes cell proliferation and G2/M transition by inhibiting CDK1 ubiquitination and stabilizing CDK1.
Yuya Ono   +14 more
wiley   +1 more source

Bortezomib

open access: yesIndian Journal of Medical and Paediatric Oncology, 2010
openaire   +4 more sources

Prognostic Impact of the Hevylite Assay in Patients With IgG or IgA Multiple Myeloma Treated Within the GMMG‐MM5 Trial

open access: yesEuropean Journal of Haematology, Volume 116, Issue 3, Page 226-234, March 2026.
ABSTRACT Response assessment during treatment of multiple myeloma (MM) typically relies on immunofixation and serum electrophoresis. However, low levels of IgG and especially IgA paraprotein are difficult to quantify reliably. The Hevylite Assay quantifies the kappa and lambda fractions of IgG and IgA separately and is useful to determine response to ...
Tim Richardson   +125 more
wiley   +1 more source

Dihydrolipoamide dehydrogenase (DLD) is a novel molecular target of bortezomib

open access: yesCell Death and Disease
Proteasome inhibitors (PIs), such as bortezomib and calfizomib, were backbone agents in the treatment of multiple myeloma (MM). In this study, we investigated bortezomib interactors in MM cells and identified dihydrolipoamide dehydrogenase (DLD) as a ...
Yu Feng   +14 more
doaj   +1 more source

Why We Do Not Recommend That People With High‐Risk Smoldering Myeloma Receive Treatment

open access: yes
American Journal of Hematology, Volume 101, Issue 3, Page 409-412, March 2026.
Ghulam Rehman Mohyuddin   +3 more
wiley   +1 more source

Rapid Recognition of Carfilzomib‐Induced Thrombotic Microangiopathy and Early Application of Eculizumab Successfully Rescued Two Relapsed Myeloma Patients

open access: yes
Chronic Diseases and Translational Medicine, Volume 12, Issue 1, Page 63-68, March 2026.
Zi Wang   +6 more
wiley   +1 more source

Neuronal metabolism role in ketogenic diet improvements in bortezomib-induced painful peripheral neuropathy mouse model. [PDF]

open access: yesPain Rep
Heslop LL   +8 more
europepmc   +1 more source

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