Results 151 to 160 of about 53,199 (230)

PKA‐Mediated Proteasome Activation Protects Against Cardiac Remodeling and Heart Failure During Systolic Overload

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Systolic overload increases the synthesis of cardiac proteins, both misfolded and native, leading to cardiac hypertrophy and elevated proteostasis burden. Meanwhile, systolic overload also increases Ser14‐RPN6 phosphorylation (pS14‐RPN6), thereby increasing proteasome (Psm) proteolytic capacity and meeting the increased demand for protein degradation ...
Md. Salim Ahammed, Penglong Wu, Yifan Wang, Liuqing Yang, Jack O. Sternburg, Faqian Li, Jinbao Liu, Xuejun Wang   +7 more
wiley   +1 more source

Persistence to Multiple Myeloma Treatments Given at First Relapse-Results From the Australian Real-World OPTIMISE Study. [PDF]

EJHaem
Buescher F, Su S, Waterhouse B, Pinto C.
europepmc   +1 more source

When All Else Fails: Complete Remission with Bortezomib in a Child with Life-Threatening Refractory Autoimmune Hemolytic Anemia [PDF]

Turk J Haematol
Demircioğlu F, Avcı Z, Akalın İ, Demircioğlu AS, Tavil B.   +4 more
europepmc   +1 more source

Bortezomib Suppresses Abnormal Proliferation, Migration, and Phenotypic Switching of Aortic Smooth Muscle Cells. [PDF]

Acta Cardiol Sin
Tseng YH, Wang LY, Kuan YH, Huang SE, Sulistyowati E, Tsai SP, Yeh JL, Hsu JH.   +7 more
europepmc   +1 more source

miR-1248 enhances bortezomib-induced autophagy by targeting MEF2C/p38-MAPK signaling in multiple myeloma. [PDF]

Front Oncol
Wang W, Zhang RJ, Ma MS, Shi XM, Zhang Q, Li C, Zhang ZH, Hao CL.   +7 more
europepmc   +1 more source

Downregulation of mTORC1 Signaling is Associated with Increased Sensitivity to Protein Synthesis Perturbations in Multiple Myeloma. [PDF]

ACS Omega
Singha D, Choudhury D, Mondal M, Hossain J, Vedeshachaitanya B, Malakar P.   +5 more
europepmc   +1 more source

Synchronous Coexistence of JAK2 V617F-Positive Essential Thrombocythemia and IgG Kappa Multiple Myeloma in an Octogenarian Patient: A Case Report. [PDF]

Case Rep Med
Ribero-Vargas M, Ahumada-Córdoba F, Silva-Pérez NM, Ribero-Vargas D.   +3 more
europepmc   +1 more source

Efficacy and Safety of Daratumumab-Based Regimens in Multiple Myeloma: A Systematic Review and Meta-Analysis of Phase III Randomized Controlled Trials. [PDF]

EJHaem
Khan AM, Ajmal H, Khalid M, Babar W, Shafaqat U, Fida T, Hassan MA, Fatima S, Akram AS, Segawa F.   +9 more
europepmc   +1 more source

Non-coding RNAs as predictive factors of oncological outcomes in plasma cell myeloma. [PDF]

Oncol Rev
Bogdanowicz-Żeleźniak A, Moniczewska N, Korpysz M, Szudy-Szczyrek A, Mlak R.   +4 more
europepmc   +1 more source

Lenalidomide-Associated Rhabdomyolysis Progressing to Bilateral Compartment Syndrome and Permanent Foot Drop. [PDF]

Case Rep Oncol Med
Iyer K, Chetan S, Arkala A, Siegel CS, Gadi B, Popu C, Oke V, Cadiz BS.   +7 more
europepmc   +1 more source