Results 131 to 140 of about 1,880 (174)
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Metabolism of Boswellic Acids in Vitro and in Vivo
Drug Metabolism and Disposition, 2008Boswellia serrata resin dry extract is among the few herbal remedies designated with an orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (BAs), the main active ingredients of B. serrata extracts, have potent anti-inflammatory properties, and may represent promising agents for the treatment of inflammatory ...
Phillip, Krüger +9 more
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Anti-inflammatory actions of boswellic acids
Phytomedicine, 1996Boswellic acids (BA) demonstrated dose-related anti-inflammatory activity (AIA) in acute tests of carrageenan-, histamine- and dextran-induced edema in rats and mice. It elicited inhibitory action on vascular permeability in mice induced by acetic acid.
G B, Singh, S, Singh, S, Bani
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Toxicity and safety evaluation of boswellic acids
Phytomedicine, 1996The acute, sub-acute and chronic toxicity studies on boswellic acids (BAs) were carried out on mice, rats and monkeys. BAs did not cause any mortality in rats and mice when administered orally and intraperitoneally in doses up to 2 g/kg. Daily oral administration of BAs in three doses (low and very high) to rats and monkeys revealed no significant ...
G B, Singh, S, Bani, S, Singh
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Modulation of Pgp Function by Boswellic Acids
Planta Medica, 2006Boswellic acids, the main active ingredients of Boswellia serrata, are gaining more and more importance in the treatment of peritumoural oedema and chronic inflammatory diseases. They may be even considered as alternative drugs to corticosteroids in reducing cerebral peritumoural oedema. An important focus for drugs acting in the central nervous system
Claudia-Carolin, Weber +4 more
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Boswellic Acids: Biological Actions and Molecular Targets
Current Medicinal Chemistry, 2006Gum resin extracts of Boswellia species have been traditionally applied in folk medicine for centuries to treat various chronic inflammatory diseases, and experimental data from animal models and studies with human subjects confirmed the potential of B. spec extracts for the treatment of not only inflammation but also of cancer.
Daniel, Poeckel, Oliver, Werz
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Boswellic acids as promising agents for the management of brain diseases
Life Sciences, 2023Boswellic acid (BA)s are pentacyclic triterpenic acids present in gum resin of Boswellia species (such as B. serrata and B. carterii). They possess a variety of pharmacological effects such as anti-inflammatory, anti-oxidant, and anti-excitotoxic effects. These properties may have potential therapeutic implication in neurological disorders.
Arezoo Rajabian +4 more
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The stereochemistry of the boswellic acids
Phytochemistry, 1968Abstract The configuration of the substituents at C(3), C(4), C(5), C(8), C(10), C(13) and C(17) in α- and β-boswellic acids have been shown to be identical by an ursane-oleanane interconversion. Synthetic and dehydration studies of the C(3) epimeric alcohols have confirmed the axial configuration of the hydroxyl group in the boswellic acids and ...
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Acta Physiologiae Plantarum, 2012
Boswellia serrata Roxb. is a source of several bioactive triterpenoids. Boswellic acid, obtained from oleo-gum resin of the tree, is a major potentially bioactive and medicinal compound. Unrestricted exploitation of its natural resource has led to its listing among the threatened and endangered species.
Ravi Ghorpade +2 more
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Boswellia serrata Roxb. is a source of several bioactive triterpenoids. Boswellic acid, obtained from oleo-gum resin of the tree, is a major potentially bioactive and medicinal compound. Unrestricted exploitation of its natural resource has led to its listing among the threatened and endangered species.
Ravi Ghorpade +2 more
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Effect of Boswellic acids on T cell proliferation and activation
International Immunopharmacology, 2023Boswellic acids have been recognized as anti-inflammatory and immunomodulatory agents with potentials to control autoimmune and inflammatory diseases. However, their effects on T cell proliferation and activation are not fully elucidated. In this study, we investigated effects of individual compounds including β-Boswellic acids (β-BA), 11-keto-β ...
Abdo Meyiah +4 more
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Boswellic acids: a group of medicinally important compounds
Nat. Prod. Rep., 2009This review, containing over 276 references, covers the progress made in the chemistry and bioactivity of this important group of triterpenoids. Though initially known for their anti-inflammatory and anti-arthritic activities through a unique 5-LO inhibition mechanism, boswellic acids have recently attained significance due to their anti-cancer ...
Bhahwal Ali, Shah +2 more
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