Results 21 to 30 of about 69 (68)
A procedure using low‐cost reagents to prepare allogeneic platelet gel from standard platelet units
Abstract Background and Objectives Highly effective procedures for the preparation of allogeneic platelet gel (PG) use Ca‐gluconate and batroxobin, an expensive commercial reagent. In this preliminary study, we explored the use of the plasmin‐inhibitor, low‐cost drug tranexamic acid (TXA) in place of batroxobin, based on the literature supporting TXA ...
Larysa Mykhailova+8 more
wiley +1 more source
We provide boundaries of the Sierra Madre Oriental in Mexico through a multi‐taxa endemicity analysis. ABSTRACT The Sierra Madre Oriental (SMO) is a significant mountain range and one of Mexico's 14 biogeographical provinces. Its delimitation has been debated.
Irene Goyenechea Mayer‐Goyenechea+5 more
wiley +1 more source
Prey specificity of predatory venoms
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek+2 more
wiley +1 more source
Ontogenetic variability of Bothrops atrox and Bothrops asper snake venoms from Colombia
The lancehead snakes Bothrops asper and Bothrops atrox inflict 70-90% of the 3000 bites reported every year in Colombia. In this work, the venoms of B. atrox from Meta (Villavicencio, 33 specimens) and B. asper from Antioquia (San Carlos, 45 specimens), all of them born in captivity, were obtained at different ages (0-6 months; 1, 2 and 3-years old ...
Saldarriaga Córdoba, Mónica María+5 more
openaire +5 more sources
Abstract Capturing data on the life of fossorial vertebrates is difficult since access to the subterranean environment is made unfeasible by its density and opacity. Collecting specimens is only possible through excavation work, causing damage or even death to the specimens.
Carlos Jared+6 more
wiley +1 more source
Isolation of basic myotoxins from Bothrops Moojeni and Bothrops Atrox snake venoms
Three myotoxins, one from the venom of Bothrops atrox and two from the venom of B. moojeni, were isolated by ion-exchange chromatography on CM-Sephadex C-25. The three toxins are basic proteins with an estimated mol. wt of about 13,500, and similar amino acid compositions.
Lomonte, Bruno+7 more
openaire +5 more sources
Quantification of snake venom proteomes by mass spectrometry‐considerations and perspectives
Abstract The advent of soft ionization mass spectrometry‐based proteomics in the 1990s led to the development of a new dimension in biology that conceptually allows for the integral analysis of whole proteomes. This transition from a reductionist to a global‐integrative approach is conditioned to the capability of proteomic platforms to generate and ...
Juan J. Calvete+4 more
wiley +1 more source
Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in reports on the effectiveness of this antivenom to treat victims bitten by B. atrox snakes.
Luis Roberto de Camargo Gonçalves+7 more
openaire +5 more sources
Batroxobin can inhibit platelet aggregation, degrade insoluble fibrinogen, dissolve soluble fibrin, and prolong TT and APTT which makes it play a stable role in the effective treatment of CVT. Batroxobin can slow down the changes in coagulation indicators, which makes it not increase the risk of adverse events, especially bleeding.
Duo Lan+9 more
wiley +1 more source
Antitumor effect of Bothrops jararaca venom [PDF]
Many experimental studies have been carried out using snake venoms for the treatment of animal tumors, with controversial results. While some authors have reported an antitumor effect of treatment with specific snake venom fractions, others have reported no effects after this treatment.
da Silva, R. J.+3 more
openaire +4 more sources