Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, [PDF]
Background Understanding the processes that drive the evolution of snake venom is a topic of great research interest in molecular and evolutionary toxinology. Recent studies suggest that ontogenetic changes in venom composition are genetically controlled
Angulo, Yamileth +10 more
core +2 more sources
Snake antivenom for snake venom induced consumption coagulopathy [PDF]
Background Snake venom induced consumption coagulopathy is a major systemic effect of envenoming. Observational studies suggest that antivenom improves outcomes for venom induced consumption coagulopathy in some snakebites and not others. However, the
Allen +18 more
core +2 more sources
Inflammatory infiltrate in skeletal muscle injected with Bothrops asper venom.
The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied. The venom induced myonecrosis, and a prominent decrease in muscle levels of creatine kinase (CK) as early as 3 hr after envenomation. Inflammatory infiltrate was scarce by 6 hr.
Gutiérrez, José María +2 more
openaire +4 more sources
The venom of Bothrops asper induces severe coagulation disturbances in accidentally envenomed humans. However, only few studies have been conducted to identify components that interact with the hemostatic system in this venom.
Adrián Pinto +3 more
doaj
Components with phospholipase A2 activity were isolated by gel filtration and cationic exchange chromatography from the venom of Bothrops asper snakes from Chiriguaná, Colombia (9°22´N; 73°37´W).
J. Ramírez-Avila +3 more
doaj +1 more source
Antibody neutralization of a myotoxin from the venom of Bothrops asper (terciopelo)
Neutralization of biological activities of B. asper myotoxin by a monospecific anti-myotoxin rabbit serum and polyvalent antivenom was studied. Both antisera neutralized myotoxic, phospholipase A and lethal activities of myotoxin, whereas edema-forming activity of myotoxin was not neutralized by these antisera.
Lomonte, Bruno +3 more
openaire +4 more sources
Cumplimiento del protocolo para el manejo de intoxicaciones agudas por mordedura de serpiente en pacientes atendidos en el Hospital Victoria Motta-Jinotega, 2014-2015 [PDF]
Según la OMS hasta cinco millones de personas sufren cada año mordeduras de serpiente. Para Latinoamérica se estiman 150,000 accidentes ofídicos y la muerte de 5,000 personas por esta causa (León, 2014).
Díaz Estrada, Adonis Francisco +1 more
core
Haemotixic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise [PDF]
Snake venoms are mixtures of numerous proteinacious components that exert diverse functional activities on a variety of physiological targets. Because the toxic constituents found in venom vary from species to species, snakebite victims can present with ...
Abubakar +97 more
core +4 more sources
Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom
Local tissue damage represents a serious consequence of Bothrops asper envenomations. It encompasses a complex series of alterations, including myonecrosis, dermonecrosis, hemorrhage and edema. Due to its rapid development it is difficult to neutralize by antivenoms, especially if there is a delay in serotherapy.
Gutiérrez, José María +5 more
openaire +4 more sources
Algunas especies de la familia Heliconaceae han demostrado capacidad neutralizante parcial/total de las actividades letal, hemolítica indirecta, hemorrágica, proteolítica, coagulante, mionecrosante y edematizante del veneno de Bothrops asper (mapaná ...
Sebastián ESTRADA G +5 more
doaj

