Results 11 to 20 of about 3,337 (190)

Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper [PDF]

Nature Communications
Improved therapies are needed against snakebite envenoming, which kills and permanently disables thousands of people each year. Recently developed neutralizing monoclonal antibodies against several snake toxins have shown promise in preclinical rodent ...
Christoffer V. Sørensen, Julián Fernández, Anna Christina Adams, Helen H. K. Wildenauer, Sanne Schoffelen, Line Ledsgaard, Manuela B. Pucca, Michael Fiebig, Felipe A. Cerni, Tulika Tulika, Bjørn G. Voldborg, Aneesh Karatt-Vellatt, J. Preben Morth, Anne Ljungars, Lise M. Grav, Bruno Lomonte, Andreas H. Laustsen   +16 more
doaj   +6 more sources

Bothrops asper (Terciopelo) scavenging behavior [PDF]

, 2009
This is the final version of the article. It first appeared from Society for the Study of Amphibians and Reptiles via https://www.zenscientist.com/index.php/pdflibrary2/func-finishdown/129/This research was sponsored by the Gates Cambridge ...
Logan, Corina J, Montero, Christopher
core   +5 more sources

A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins [PDF]

Plant Biotechnology Journal, Volume 16, Issue 3, Page 727-736, March 2018., 2018
Antivenoms developed from the plasma of hyperimmunized animals are the only effective treatment available against snakebite envenomation but shortage of supply contributes to the high morbidity and mortality toll of this tropical disease.
Arnold, Beerli, Bendandi, Bolanos, Chippaux, Elena, Frauches, Gene, Graham, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Gutierrez, Harrison, Julve, Laustsen, Laustsen, Lavonas, Marillonnet, Marillonnet, Paul, Paul, Pla, Qiu, Ramos, Rasmussen, Sarrion-Perdigones, Segura, Soller, Stock, Stoger, Syller, Theakston, Walwyn, Wang, Zheng   +38 more
core   +3 more sources

Accidente ofídico causado por Bothrops Asper

Revista Ciencias Biomédicas, 2013
Introduction: The snake bite of the genus Bothrops is an important cause of ophidic accident in Colombia, with high morbidity and mortality. Clinical case: A case of bite by the snake Bothrops Asper, which was classified as mild grade of poisoning at ...
Galofre-Ruiz Mario David
doaj   +2 more sources

Feeding ecology of the Terciopelo pit viper snake (Bothrops asper) in Ecuador. [PDF]

PeerJ, 2023
Thoroughly documenting prey items and diet composition is crucial for understanding a predator’s role in the ecosystem. In gape restricted predators, such as snakes, documenting and analyzing the type and size of the prey is important to interpret their ecological role.
Loaiza-Lange A, Székely D, Torres-Carvajal O, Tinoco N, Salazar-Valenzuela D, Székely P.   +5 more
europepmc   +4 more sources

Hematology, Clinical Biochemistry, and Blood Cell Morphology Features of Captive Bothrops jararaca From Southeast Brazil. [PDF]

Vet Clin Pathol
ABSTRACT Background Snakebite envenomation is a worldwide public health issue, particularly relevant to low and middle‐income countries. Bothrops spp. antivenom is needed for snakebite treatment, which requires the maintenance of healthy snakes in captivity.
Alcantara AO, Reis BMM, Fonseca JG, Sousa MAC, Roxo VHA, Souza GJ, Castro FFA, Souza GN, Fernandes J, Lemos ERS, Souza AM.   +10 more
europepmc   +2 more sources

Design of Fab-based chimeric antibodies against Bothrops asper toxins [PDF]

, 2016
Snakebite is one of the world’s most neglected tropical diseases, with an estimated 5 million bites per year, resulting in about 125.000 deaths. The only current treatment for snakebite envenoming is antiserum derived from the blood of immunized mammals(typically horses).
Andersen, Mikael Rørdam, B. Hallgren, Malte, H. Dam, Søren, Kilstrup, Mogens, Laustsen, Andreas Hougaard, M. Haack, Aleksander, Martos Esteban, Andrea, U. W. Friis, Rasmus   +7 more
core   +2 more sources

Case Report: Hemothorax in Envenomation by the Viperid Snake Bothrops asper. [PDF]

Am J Trop Med Hyg, 2019
Bothrops asper, a highly venomous pit viper distributed from Colombia and northwestern Peru in South America to southern Mexico, is responsible for most snake bites in Central America, affecting especially young agricultural workers. A 17-year-old male from a rural area in northern Honduras was admitted at San Francisco Hospital after a B.
Pinto LJ, Lee Fernández L, Gutiérrez JM, Simón DS, Ceballos Z, Aguilar LF, Sierra M.   +6 more
europepmc   +4 more sources

The Incidence of Infection Complicating Snakebites in Tropical Australia: Implications for Clinical Management and Antimicrobial Prophylaxis

Journal of Tropical Medicine, Volume 2023, Issue 1, 2023., 2023
Objective. To define the incidence of infection following snakebite in tropical Australia and the resulting implications for the routine prescription of prophylactic antibiotics. Methods. A retrospective study of all individuals presenting to Cairns Hospital, a tertiary referral hospital in tropical Australia, after a snakebite between December 2013 ...
Laura K. Smith, John Vardanega, Simon Smith, Julian White, Mark Little, Josh Hanson, Qin-Xiu Zhang   +6 more
wiley   +1 more source

Anti‐Metalloprotease P‐I Single‐Domain Antibodies: Tools for Next‐Generation Snakebite Antivenoms

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
In order to address the global antivenom crisis, novel antivenoms need to present high therapeutic efficacy, broad neutralization ability against systemic and local damage, sufficient safety, and cost‐effectiveness. Due to biological characteristics of camelid single‐domain antibodies (VHH) such as high affinity, their ability to penetrate dense ...
Marcela C. S. Silva, Soraya S. Pereira, Marilia P. Gouveia, Marcos B. Luiz, Rosa M. O. Sousa, Anderson M. Kayano, Aleff F. Francisco, Nidiane D. R. Prado, Leandro S. M. Dill, Marcos R. M. Fontes, Fernando B. Zanchi, Rodrigo G. Stabeli, Andreimar M. Soares, Juliana P. Zuliani, Carla F. C. Fernandes, Carla F. C. Fernandes   +15 more
wiley   +1 more source