Results 21 to 30 of about 3,386 (204)

The Incidence of Infection Complicating Snakebites in Tropical Australia: Implications for Clinical Management and Antimicrobial Prophylaxis

Journal of Tropical Medicine, Volume 2023, Issue 1, 2023., 2023
Objective. To define the incidence of infection following snakebite in tropical Australia and the resulting implications for the routine prescription of prophylactic antibiotics. Methods. A retrospective study of all individuals presenting to Cairns Hospital, a tertiary referral hospital in tropical Australia, after a snakebite between December 2013 ...
Laura K. Smith, John Vardanega, Simon Smith, Julian White, Mark Little, Josh Hanson, Qin-Xiu Zhang   +6 more
wiley   +1 more source

Anti‐Metalloprotease P‐I Single‐Domain Antibodies: Tools for Next‐Generation Snakebite Antivenoms

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
In order to address the global antivenom crisis, novel antivenoms need to present high therapeutic efficacy, broad neutralization ability against systemic and local damage, sufficient safety, and cost‐effectiveness. Due to biological characteristics of camelid single‐domain antibodies (VHH) such as high affinity, their ability to penetrate dense ...
Marcela C. S. Silva, Soraya S. Pereira, Marilia P. Gouveia, Marcos B. Luiz, Rosa M. O. Sousa, Anderson M. Kayano, Aleff F. Francisco, Nidiane D. R. Prado, Leandro S. M. Dill, Marcos R. M. Fontes, Fernando B. Zanchi, Rodrigo G. Stabeli, Andreimar M. Soares, Juliana P. Zuliani, Carla F. C. Fernandes, Carla F. C. Fernandes   +15 more
wiley   +1 more source

Fasciotomía tras emponzoñamiento por Bothrops asper

Revista Medica Sinergia, 2021
Bothrops asper es responsable de hasta el 80% del ofidismo del norte de Sudamérica, teniendo su veneno una acción proteolítica y coagulante sobre el miembro afectado. Se realiza un estudio descriptivo, con análisis retrospectivo, con identificación taxonómica y revisión de la literatura.
Carlos Tonos, Luis Eduardo Traviezo Valles, Carlos Pacheco   +2 more
openaire   +1 more source

Light Emitting Diode Photobiomodulation Enhances Oxidative Redox Capacity in Murine Macrophages Stimulated with Bothrops jararacussu Venom and Isolated PLA2s

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
Photobiomodulation therapy associated with conventional antivenom treatment has been shown to be effective in reducing the local effects caused by bothropic venoms in preclinical studies. In this study, we analyzed the influence of photobiomodulation using light emitting diode (LED) on the oxidative stress produced by murine macrophages stimulated with
Valdison Pereira dos Reis, Sulamita da Silva Setúbal, Alex A. Ferreira e Ferreira, Hallison Mota Santana, Milena Daniela Souza Silva, Ortência De Oliveira Sousa, Charles Nunes Boeno, Andreimar M. Soares, Stella R. Zamuner, Juliana P. Zuliani, Valeria Pasciu   +10 more
wiley   +1 more source

Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity

Toxicon: X, 2020
A bioactive compound isolated from the stem extract of Aristolochia sprucei through High Performance Liquid Chromatography (HPLC) was identified via Nuclear Magnetic Resonance (NMR) as the aristolochic acid (AA). This compound showed an inhibitory effect
Isela I. González Rodríguez, Aleff F. Francisco, Leandro S. Moreira-Dill, Aristides Quintero, César L.S. Guimarães, Carlos A.H. Fernandes, Agnes A.S. Takeda, Fernando B. Zanchi, Cléopatra A.S. Caldeira, Paulo S. Pereira, Marcos R.M. Fontes, Juliana P. Zuliani, Andreimar M. Soares   +12 more
doaj   +1 more source

Parasitismo de Porocephalus (Penstastomida: Porocephalidae) en Bothrops asper (Viperidae) en Ecuador

Biota Colombiana, 2023
Se reporta la presencia de pentastómidos del género Porocephalus en especímenes de Bothrops asper que reposan en la colección Herpetológica del Instituto Nacional de Biodiversidad en Ecuador.
Miguel Urgilés-Merchán, Gabriela Lagla-Chimba, Rafael Mena-Orbe, Mario Yanez-Muñoz   +3 more
doaj   +1 more source

PHYLOGENY OF SOME MIDDLE AMERICAN PITVIPERS BASED ON A CLADISTIC ANALYSIS OF MITOCHONDRIAL 12S AND 16S DNA SEQUENCE INFORMATION [PDF]

, 1999
The cladistic relationships of several Middle American pitvipers representing the genera Bothrops (sensu stricto), Bothriechis, Cerrophidion, Lachesis and Porthidium were determined using mitochondrial 12S and 16S DNA sequence information.
Crother, Brian I., Werman, Steven D., White, Mary E.   +2 more
core   +2 more sources

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B., Lakshminarayanan, Karthik, Layfield, Harry J., Mehmi, Amita, Patel, Ketan, Ravishankar, Divyashree, Salim, Anika, Sonavane, Medha, Trim, Steven A., Vaiyapuri, Rajendran, Vaiyapuri, Sakthivel, Vallance, Thomas M., Williams, Harry F.   +12 more
core   +1 more source

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]

, 2015
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
A Osaka, A Rucavado, A Rucavado, AF Pinto, AK Oliveira, Alexandra Rucavado, AM Moura-da-Silva, AM Moura-da-Silva, Ana Moura, BG Fry, C Baldo, Cristina Herrera, DB Gould, Diego Morazán, E Camacho, EN Baramova, EN Baramova, EN Baramova, J Durban, Jay W. Fox, JJ Calvete, JM Gutiérrez, JM Gutiérrez, JM Gutiérrez, JM Gutiérrez, José María Gutiérrez, Juan J. Calvete, JW Fox, Jéssica Kele A. Macêdo, K Kühn, K Kühn, L Watanabe, Libia Sanz, Mathieu-Benoit Voisin, N Jiménez, NR Casewell, NR Casewell, NR Casewell, PD Yurchenco, PD Yurchenco, R Timpl, SM Serrano, SM Serrano, SM Serrano, Sussan Nourshargh, SV Costes, T Escalante, T Escalante, T Escalante, T Nikai, Teresa Escalante, UK Laemmli, WJ Wang   +52 more
core   +4 more sources

Development of a sensitive enzyme immunoassay (ELISA) for specific identification of Lachesis acrochorda venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
The snake genus Lachesis provokes 2 to 3% of snakebites in Colombia every year. Two Lachesis species, L. acrochorda and L. muta, share habitats with snakes from another genus, namely Bothrops asper and B. atrox.
V Núñez Rangel, M Fernández Culma, P Rey-Suárez, JA Pereañez   +3 more
doaj   +1 more source