Results 11 to 20 of about 1,785 (202)

A New Platelet-Aggregation-Inhibiting Factor Isolated from Bothrops moojeni Snake Venom. [PDF]

Biomed Res Int, 2017
This work reports the purification and functional characterization of BmooPAi, a platelet-aggregation-inhibiting factor fromBothrops moojenisnake venom. The toxin was purified by a combination of three chromatographic steps (ion-exchange on DEAE-Sephacel, molecular exclusion on Sephadex G-75, and affinity chromatography on HiTrap™ Heparin HP).
de Sousa BB, Mamede CCN, Matias MS, Pereira DFDC, de Queiroz MR, Dias EHV, Silva ACA, Dantas NO, Costa JO, de Oliveira F.   +9 more
europepmc   +5 more sources

Snake Venom L-Amino Acid Oxidases: Trends in Pharmacology and Biochemistry [PDF]

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
L-amino acid oxidases are enzymes found in several organisms, including venoms of snakes, where they contribute to the toxicity of ophidian envenomation.
Calderon, Leonardo A., Costa, Tássia R., da Silva, Saulo L., Fernandes, Carla F. C., Grabner, Amy N., Izidoro, Luiz Fernando M., Mendes, Mirian M., Rodrigues, Veridiana M., Soares, Andreimar M., Sobrinho, Juliana C., Stábeli, Rodrigo G., Zanchi, Fernando B., Zuliani, Juliana P.   +12 more
core   +7 more sources

Effects on cell cycle progression and cytoskeleton organization of five Bothrops spp. venoms in cell culture-based assays [PDF]

Heliyon, 2023
Snake envenomation is a neglected tropical disease. In Brazil, the Bothrops genus is responsible for about 86% of snakebite accidents. Despite extensive evidence of the cytotoxicity of snake venoms, the cellular and molecular mechanisms involved are not ...
Bianca Sayuri Takayasu, Sheila Silva Rodrigues, Carlos Eduardo Madureira Trufen, Glaucia Maria Machado-Santelli, Janice Onuki   +4 more
doaj   +2 more sources

Acidentes ofídicos causados por bothrops moojeni: relato de 37 casos [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1988
Foram estudados 37 casos de acidentes ofídicos causados por Bothrops moojeni na região de São José do Rio Preto, São Paulo, durante um período de 5 anos (outubro 1982 a setembro 1987).
João Aris Kouyoumdjian, Cristina Polizelli   +1 more
doaj   +2 more sources

Comprehensive RNA-Seq Analysis of Human Osteoclast Function in Response to Bothrops moojeni Venom Fractions: Pathways of Bone Resorption and Cytoskeletal Disruption [PDF]

Toxins
This study investigated the effects of Bothrops moojeni (B. moojeni) venom and its high- (HMM) and low-molecular mass (LMM) fractions on human osteoclast (OC) differentiation and function in vitro, aiming to identify novel therapeutics for bone disorders.
Fernanda D’Amélio, Hugo Vigerelli, Rodrigo Pinheiro Araldi, Isabel de Fátima Correia Batista, Daniel Carvalho Pimenta, Irina Kerkis   +5 more
doaj   +2 more sources

Analysis of the genus Bothrops snake venom: An inter and intraspecific comparative study [PDF]

Heliyon
The genus Bothrops are considered Category 1 of medical importance by the World Health Organization, responsible for approximately 85 % of snakebites occurring throughout Brazil.
Thais Almeida de Godoy, Eduardo Oliveira Venancio de Lima, Giovanni Perez Machado Silveira, Fabíola Souza Rodrigues, Sávio Stefani Sant'anna, Daniela Miki Hatakeyama, Kathleen Fernandes Grego, Anita Mitico Tanaka-Azevedo   +7 more
doaj   +2 more sources

Bmoo FIBMP-I: A New Fibrinogenolytic Metalloproteinase from Bothrops moojeni Snake Venom. [PDF]

ISRN Toxicol, 2012
A new fibrinogenolytic metalloproteinase (Bmoo FIBMP-I) was purified fromBothrops moojenisnake venom. This enzyme was isolated through a combination of three chromatographic steps (ion-exchange, molecular exclusion, and affinity chromatography). Analyses by reverse phase chromatography, followed by mass spectrometry, showed the presence of enzyme ...
Torres FS, Rates B, Gomes MT, Salas CE, Pimenta AM, Oliveira F, Santoro MM, de Lima ME.   +7 more
europepmc   +4 more sources

Caryospora bigenetica (Apicomplexa: Eimeriidae) in South America: new hosts and distribution records [PDF]

Revista Brasileira de Parasitologia Veterinária
The coccidian Caryospora bigenetica was first described in the snake Crotalus horridus (Viperidae) from United States of America. This study represents the first record of the occurrence of C. bigenetica in snakes in South America.
Lúcio André Viana, Kamilla Costa Mecchi, Leonardo França do Nascimento, Heitor Miraglia Herrera, Paula Helena Santa-Rita, Marcos Tobias de Santana Miglionico, Rhaiza Gama Esteves, Anibal Rafael Melgarejo Gimenez, Fernando Paiva   +8 more
doaj   +2 more sources

Effects of Bothrops moojeni venom on Leishmania amazonensis promastigote forms [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
Abstract: In the present work, the effect of Bothrops moojeni venom fractions on Leishmania promastigotes was evaluated. The snake venom was fractionated into five protein fractions (E1 to E5), by ion exclusion chromatography, that were used to treat Leishmania amazonensis and Leishmania braziliensis promastigote forms whereas the viability and nitric ...
P Castilhos, CG Pereira, ALN Silva, DR Napolitano, F Oliveira, MA Souza   +5 more
doaj   +4 more sources

Ontogenetic and sexual differences in the venom of Bothrops moojeni: insights from a litter and its mother [PDF]

Brazilian Journal of Biology
Variability in snake venom composition is well-documented and crucial for understanding snake ecology and predicting snakebites. In this study, we characterize the venom composition and biological activities of newborn female and male Bothrops moojeni ...
S. C. Ferreira-Rodrigues, R. C. C. Silva, M. Trevisan, P. S. M. Rodrigues, T. H. M. Del-Rei, L. F. Sousa, A. R. G. Vilarinho, C. A. Lima, J. L. Rodrigues, M. M. R. Silva, A. M. Moura-da-Silva, S. S. Sant’Anna, C. S. Seibert   +12 more
doaj   +3 more sources