Results 61 to 70 of about 457,707 (309)

The role of Internal Solitary Waves on deep-water sedimentary processes. The case of up-slope migrating sediment waves off the Messina Strait [PDF]

open access: yes, 2016
Subaqueous, asymmetric sand waves are typically observed in marine channel/canyon systems, tidal environments, and continental slopes exposed to strong currents, where they are formed by current shear resulting from a dominant unidirectional flow ...
Casalbore, Daniele   +8 more
core   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

A complete and continuous core record of deep-water mass transport deposits

open access: yesFrontiers in Marine Science
Mass transport deposits are a fundamental component of deep-water sedimentary systems and play a crucial role in the transportation of sediments from continental slopes to deep-sea basins.
Cong Cheng   +11 more
doaj   +1 more source

General characteristics of current in front of Port Said, Egypt

open access: yesEgyptian Journal of Aquatic Research, 2017
This paper is a preliminary investigation of the general characteristics of the current in front of the coastal Mediterranean city: Port Said, Egypt. The study of the current regime in front of Port Said helps environmental engineers to tackle problems ...
Mohamed S. Elsharkawy   +2 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Flavor-Safe Light Squarks in Higgs-Anomaly Mediation

open access: yes, 2018
We consider a simple setup with light squarks which is free from the gravitino and SUSY flavor problems. In our setup, a SUSY breaking sector is sequestered from the matter and gauge sectors, and it only couples to the Higgs sector directly with ...
Yanagida, Tsutomu T.   +2 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Hybrid turbidite–contourite systems in the modern Tarakan Basin: seismic sedimentology and analogue for subsurface storage

open access: yesFrontiers in Earth Science
Hybrid turbidite–contourite systems are present where gravity-driven and bottom-current processes interact. Although recent studies have advanced our understanding, deciphering the relative roles of downslope and alongslope processes in shaping the deep ...
Harya Dwi Nugraha   +2 more
doaj   +1 more source

Current effects on scattering of surface gravity waves by bottom topography

open access: yes, 2005
Scattering of random surface gravity waves by small amplitude topography in the presence of a uniform current is investigated theoretically. This problem is relevant to ocean waves propagation on shallow continental shelves where tidal currents are often
Ardhuin, Fabrice, Magne, Rudy
core   +3 more sources

The influence of mask thickness on charging damage during overetching [PDF]

open access: yes, 1997
Feature-scale charging simulations during gate electrode overetching in high-density plasmas reveal that the thickness of the insulating mask plays a critical role in charging damage. When thinner masks are used, the electron irradiance of the conductive
Giapis, Konstantinos P.   +1 more
core   +2 more sources

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