Results 101 to 110 of about 48,590 (264)

Botulinum toxin use in patients with neurological disorders: A U.S.‐based claims database analysis

PM&R, EarlyView.
Abstract Background and Objective Real‐world evidence describing long‐term persistency with botulinum toxin (BoNT) therapy is limited. We assessed treatment patterns and persistency with BoNT in clinical practice over 2 years. Design Retrospective, longitudinal, claims database analysis. Setting Medical claims data from the Merative MarketScan database
David M. Simpson, Jonathan Bouchard, Simon Page, Seth Goldfarb, Atul T. Patel   +4 more
wiley   +1 more source

Evaluating the efficacy of obturator cryoneurolysis for hip adductor spasticity: An observational, prospective study

PM&R, EarlyView.
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae, Mahdis Hashemi, Paul Winston   +2 more
wiley   +1 more source

The predictive nature of diagnostic nerve blocks for lower extremity spasticity management with botulinum toxin and neurotomy: A systematic review

PM&R, EarlyView.
Abstract Introduction/Objective Diagnostic nerve blocks (DNBs) involve the injection of anesthetic around peripheral nerves to temporarily reduce motor tone. Although they are used clinically to inform spasticity treatment with neurotomy and chemodenervation, there is little research exploring the predictive nature of DNBs.
Katherine Archibold, Jeremy Slayter, Emily M. Krauss, Alexander Whelan   +3 more
wiley   +1 more source

The use of intradetrusor botulinum toxin in the geriatric population

BJUI Compass
Objectives This study aims to explore the impact of age on long‐term outcomes associated with intradetrusor botulinum toxin (BoNT) usage (up to four cycles) in elderly patients with refractory overactive bladder syndrome (OAB).
William Chui, Alvaro Bazo, Henry H. Yao, Joshua Kealey, Lana Pepdjonovic, Helen E. O'Connell, Johan Gani, Richard Parkinson   +7 more
doaj   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

BOTULINUM TOXIN [PDF]

Australian and New Zealand Journal of Ophthalmology, 1988
openaire   +2 more sources

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest
Lin‐Lin Lan, Qiu‐Rong Yang, Pei‐Yun Zhuang   +2 more
wiley   +1 more source

Clinical Characteristics and Treatment Patterns of Hyperhidrosis in Northern Hokkaido: A Single‐Center Retrospective Descriptive Study

The Journal of Dermatology, EarlyView.
ABSTRACT Hyperhidrosis is a common condition associated with a substantial negative impact on the quality of life. Several studies have described the clinical characteristics and disease burden of patients with hyperhidrosis in Japan. However, comparable real‐world clinical data on hyperhidrosis from Hokkaido remain limited. We therefore evaluated real‐
Mari Kishibe, Aiko Noguchi, Marika Matsuya, Kou Matsumoto, Satomi Igawa, Yasuyuki Fujita   +5 more
wiley   +1 more source

Tale of Two Centres—Exploring Bedside Challenges to Implementing a Clinical Quality Registry for Abdominal Wall Hernias in Metropolitan Australia

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background In an effort to improve hernia care and mesh product surveillance, the Australia and New Zealand Hernia Society (ANZ Hernia) has been setting up a prototype binational learning healthcare system virtual clinical quality registry (CQR) for clinical use.
Edward Young, Doug Fenton‐Lee, Julian Süsstrunk, Jorgen Ferguson, Matthew Amprayil, Yijie Yin, Rabieh Abu Assi, Alex Karatassas, Sanjeev Khurana, Chrys Hensman, Andrew Tse, Hamish Urquhart, Reginald V. N. Lord, Jean Wong, Darren Tonkin, Markus Trochsler, Guy J. Maddern   +16 more
wiley   +1 more source