Results 1 to 10 of about 1,270,897 (309)

Novel and effective screening system for recombinant protein production in CHO cells

Scientific Reports
At present, biopharmaceuticals have received extensive attention from the society, among which recombinant proteins have a good growth trend and a large market share.
Junhe Zhang, Wenwen Yang, Liao Zhang, Wenqing Li, Xi Zhang, Xiaoyin Wang, Tianyun Wang   +6 more
doaj   +1 more source

Newcastle Disease Virus Fusion and Haemagglutinin-Neuraminidase Gene Divergence: Implications for Vaccines

Veterinary Sciences
Avian orthoavulavirus 1 (AOaV-1), commonly known as Newcastle disease virus (NDV), despite widespread vaccination, remains a significant threat to domestic chickens (Gallus gallus domesticus).
Ravendra P. Chauhan, Boguslaw Szewczyk
doaj   +1 more source

Unraveling the impact of SARS-CoV-2 mutations on immunity: insights from innate immune recognition to antibody and T cell responses

Frontiers in Immunology
Throughout the COVID-19 pandemic, the emergence of new viral variants has challenged public health efforts, often evading antibody responses generated by infections and vaccinations. This immune escape has led to waves of breakthrough infections, raising
Rafael Bayarri-Olmos, Rafael Bayarri-Olmos, Adrian Sutta, Adrian Sutta, Anne Rosbjerg, Anne Rosbjerg, Mie Mandal Mortensen, Charlotte Helgstrand, Per Franklin Nielsen, Laura Pérez-Alós, Beatriz González-García, Laust Bruun Johnsen, Finn Matthiesen, Thomas Egebjerg, Cecilie Bo Hansen, Alessandro Sette, Alessandro Sette, Alba Grifoni, Ricardo da Silva Antunes, Peter Garred, Peter Garred   +20 more
doaj   +1 more source

Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins

Iranian Journal of Medical Sciences, 2016
Background: Macrophage immune responses are affected by the secretory proteins of Mycobacterium tuberculosis (Mtb). This study aimed to examine the immune responses of macrophages to Mtb secretory antigens, namely ESAT-6, CFP-10, and ESAT-6/CFP-10 ...
Atefeh Seghatoleslam, Mina Hemmati, Saeedeh Ebadat, Bahram Movahedi, Zohreh Mostafavi-Pour   +4 more
doaj  

IFN-γ and IL-2 Responses to Recombinant AlaDH against ESAT-6/CFP-10 Fusion Antigens in the Diagnosis of Latent versus Active Tuberculosis Infection

Iranian Journal of Medical Sciences, 2017
Background: Discriminating latent tuberculosis infection (LTBI) from active TBI may be challenging. The objective of this study was to produce the recombinant L-alanine dehydrogenase (AlaDH) antigen and evaluate individuals with LTBI, those with active ...
Bahram Movahedi, Pooneh Mokarram, Mina Hemmati, Nader Mosavari, Razie Zare, Leila Safaee Ardekani, Zohreh Mostafavi-Pour   +6 more
doaj  

Characterization of Zika virus-like particles as potential vaccine antigens

International Journal of Infectious Diseases, 2020
G. Brzuska, A. Dziadosz, B. Szewczyk, E. Krol   +3 more
doaj   +1 more source

Human Interleukine-1 receptor antagonist:Cloning, Expression and Optimization in E.coli Host

پزشکی بالینی ابن سینا, 2014
Introduction & Objective: Interleukine-1 receptor antagonist (IL-1RA) is a powerful anti-inflammatory cytokine which limits the biological effects of IL-1.
Ghasem Barati, Hasan Mirza Hosseini, Jamshid Karimi, Fatemeh Ebrahimzadeh, Nooshin Shabab, Masoud Saidijam   +5 more
doaj  

Correction: Intravitreal injection of fibrillin 2 (Fbn2) recombinant protein for therapy of retinopathy in a retina-specific Fbn2 knock-down mouse model. [PDF]

Sci Rep
Zhang RX, Wen Y, Guo DD, Xu FR, Wang GM, Wang XR, Shi YW, Ding J, Jiang Q, Jiang WJ, Jonas JB, Bi HS.   +11 more
europepmc   +1 more source

Revisiting Enzyme Replacement Therapy for Aspartylglucosaminuria: Truncated Phosphotransferase Enhances Mannose-6-Phosphorylation and Cellular Uptake of Aspartylglucosaminidase. [PDF]

J Inherit Metab Dis
Banning A, Reznikova L, Murad A, Tikkanen R.   +3 more
europepmc   +1 more source

Evaluation of the contribution of the minor envelope complex glycoprotein 3 ectodomain to the porcine reproductive and respiratory syndrome virus 1 neutralizing antibody response. [PDF]

J Gen Virol
Hayes JWP, Edwards JC, Valdez KR, Crossley S, de Brito RCF, Munir D, Hanson K, Paschos K, Polra K, An J, Calvert JG, Di Placido MB, Lovell JF, Shattock R, Hammond JA, Owens RJ, Graham SP.   +16 more
europepmc   +1 more source