Development of an Adeno-Associated Virus-Vectored SARS-CoV-2 Vaccine and Its Immunogenicity in Mice
Owing to the outbreak of the novel coronavirus (SARS-CoV-2) worldwide at the end of 2019, the development of a SARS-CoV-2 vaccine became an urgent need.
Xi Qin +18 more
doaj +1 more source
RETRACTION: Recombinant Nanobody Against Muc1 Tandem Repeats Inhibits Growth, Invasion, Metastasis, and Vascularization of Spontaneous Mouse Mammary Tumors. [PDF]
RETRACTION: P. Merikhian, B. Darvishi, N. Jalili, M. R. Esmailinejad, A. S. Khatibi, S. M. Kalbolandi, M. Salehi, M. Mosayebzadeh, M. S. Barough, K. Majidzadeh‐A, F. Yadegari, F. Rahbarizadeh, and L. Farahmand, “Recombinant Nanobody Against Muc1 Tandem Repeats Inhibits Growth, Invasion, Metastasis, and Vascularization of Spontaneous Mouse Mammary ...
europepmc +2 more sources
Zika virus (ZIKV) is a reemerging mosquito-borne flavivirus that causes febrile illness and is also linked to Guillain-Barré syndrome as well as to microcephaly in newborns.
Gabriela Brzuska +2 more
doaj +1 more source
Use of Recombinant Virus Replicon Particles for Vaccination against Mycobacterium ulcerans Disease. [PDF]
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Kerber, Sarah +19 more
core +3 more sources
Single-crossover recombination and ancestral recombination trees [PDF]
J. Math. Biol., in press.
Baake, Ellen, von Wangenheim, Ute
openaire +3 more sources
Recombination: Homologous recombination branches out [PDF]
Homologous recombination can be divided into three key steps: strand exchange, branch migration and resolution. The identification of a protein complex that catalyses branch migration and Holliday junction resolution argues that the mechanism of homologous recombination is conserved from bacteria to man.
openaire +2 more sources
Evaluation of a reverse tetracycline inducible system in recombinant BCG to improve stability and immunogenicity [PDF]
The aim of this study is to utilise the tetracycline dependent gene regulation system to down-regulate recombinant antigen expression in BCG during the expansion of seed stocks and up-regulate expression prior to or post ...
Mbele, Prisca
core +1 more source
Development and Validation of a Reporter-Cell-Line-Based Bioassay for Therapeutic Soluble gp130-Fc
Soluble glycoprotein 130 kDa (sgp130)-Fc fusion protein, an innovative therapeutic bio-macromolecular drug specifically targeting IL-6 trans-signaling, proved to have good potential for application in the treatment of chronic inflammatory diseases.
Lei Yu +6 more
doaj +1 more source
Aptamer-Functionalized Natural Protein-Based Polymers as Innovative Biomaterials
Biomaterials science is one of the most rapidly evolving fields in biomedicine. However, although novel biomaterials have achieved well-defined goals, such as the production of devices with improved biocompatibility and mechanical properties, their ...
Alessandra Girotti +4 more
doaj +1 more source
Recombinant human preproinsulin expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus [PDF]
A novel prokaryotic expression vector pGEX-6T was designed for high-level expression of recombinant fusion protein with a histidine-hexapeptide and glutathione-S-transferase at its N-terminus and the recombinant human preproinsulin at its C-terminus ...
Seißler, Jochen +4 more
core +1 more source

