Results 11 to 20 of about 1,298,104 (309)

Development of an Adeno-Associated Virus-Vectored SARS-CoV-2 Vaccine and Its Immunogenicity in Mice

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Owing to the outbreak of the novel coronavirus (SARS-CoV-2) worldwide at the end of 2019, the development of a SARS-CoV-2 vaccine became an urgent need.
Xi Qin   +18 more
doaj   +1 more source

RETRACTION: Recombinant Nanobody Against Muc1 Tandem Repeats Inhibits Growth, Invasion, Metastasis, and Vascularization of Spontaneous Mouse Mammary Tumors. [PDF]

open access: yesMol Oncol
RETRACTION: P. Merikhian, B. Darvishi, N. Jalili, M. R. Esmailinejad, A. S. Khatibi, S. M. Kalbolandi, M. Salehi, M. Mosayebzadeh, M. S. Barough, K. Majidzadeh‐A, F. Yadegari, F. Rahbarizadeh, and L. Farahmand, “Recombinant Nanobody Against Muc1 Tandem Repeats Inhibits Growth, Invasion, Metastasis, and Vascularization of Spontaneous Mouse Mammary ...
europepmc   +2 more sources

Influence of Dosing Regimen and Adjuvant Type on the Immunogenicity of Novel Recombinant Zika Virus-Like Particles

open access: yesMicrobiology Spectrum, 2023
Zika virus (ZIKV) is a reemerging mosquito-borne flavivirus that causes febrile illness and is also linked to Guillain-Barré syndrome as well as to microcephaly in newborns.
Gabriela Brzuska   +2 more
doaj   +1 more source

Use of Recombinant Virus Replicon Particles for Vaccination against Mycobacterium ulcerans Disease. [PDF]

open access: yes, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Kerber, Sarah   +19 more
core   +3 more sources

Single-crossover recombination and ancestral recombination trees [PDF]

open access: yesJournal of Mathematical Biology, 2013
J. Math. Biol., in press.
Baake, Ellen, von Wangenheim, Ute
openaire   +3 more sources

Recombination: Homologous recombination branches out [PDF]

open access: yesCurrent Biology, 2001
Homologous recombination can be divided into three key steps: strand exchange, branch migration and resolution. The identification of a protein complex that catalyses branch migration and Holliday junction resolution argues that the mechanism of homologous recombination is conserved from bacteria to man.
openaire   +2 more sources

Evaluation of a reverse tetracycline inducible system in recombinant BCG to improve stability and immunogenicity [PDF]

open access: yes, 2011
The aim of this study is to utilise the tetracycline dependent gene regulation system to down-regulate recombinant antigen expression in BCG during the expansion of seed stocks and up-regulate expression prior to or post ...
Mbele, Prisca
core   +1 more source

Development and Validation of a Reporter-Cell-Line-Based Bioassay for Therapeutic Soluble gp130-Fc

open access: yesMolecules, 2019
Soluble glycoprotein 130 kDa (sgp130)-Fc fusion protein, an innovative therapeutic bio-macromolecular drug specifically targeting IL-6 trans-signaling, proved to have good potential for application in the treatment of chronic inflammatory diseases.
Lei Yu   +6 more
doaj   +1 more source

Aptamer-Functionalized Natural Protein-Based Polymers as Innovative Biomaterials

open access: yesPharmaceutics, 2020
Biomaterials science is one of the most rapidly evolving fields in biomedicine. However, although novel biomaterials have achieved well-defined goals, such as the production of devices with improved biocompatibility and mechanical properties, their ...
Alessandra Girotti   +4 more
doaj   +1 more source

Recombinant human preproinsulin expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus [PDF]

open access: yes, 1993
A novel prokaryotic expression vector pGEX-6T was designed for high-level expression of recombinant fusion protein with a histidine-hexapeptide and glutathione-S-transferase at its N-terminus and the recombinant human preproinsulin at its C-terminus ...
Seißler, Jochen   +4 more
core   +1 more source

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