Results 151 to 160 of about 74,841 (314)
Review of botulinum toxin type A for the prophylactic treatment of chronic daily headache
, 2007 Stefan EversDepartment of Neurology, University of Münster, Münster, GermanyAbstract: Botulinum toxin A is increasingly used in the treatment of idiopathic and symptomatic headache disorders.
Stefan Evers
core
BJU International, EarlyView.Objective To examine the role of health‐related quality of life (HRQoL) assessments and patient‐reported outcome measures (PROMs) in the economic evaluation of urological interventions, highlighting methodological challenges, and identifying areas for future development.
Mohammed El Bahnasawi +4 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Targeting KRAS for cancer therapy
British Journal of Pharmacology, EarlyView.In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia +4 more
wiley +1 more source
EPHX2 Loss Promotes CRC Migration via EET‐Dependent Chemokine Elevation and Mitochondrial Defect
Cancer Science, EarlyView.Loss of EPHX2 promotes EET accumulation, which in turn enhances CXCL and ROS production, thereby promoting the migratory and invasive abilities of CRC cells. ABSTRACT Epoxide hydrolase 2 (EPHX2) is a key enzyme in fatty acid metabolism that metabolizes epoxyeicosatrienoic acids (EETs), lipid mediators involved in inflammation, angiogenesis, and ...
Jianjun Zhu +10 more
wiley +1 more source
Exploring the Therapeutic Potential of Botulinum Toxin in Treating Post-Acne Sequelae: A Critical Review. [PDF]
Clin Cosmet Investig DermatolLiao X, Wu J, Cheng H, Zheng H, Peng Y.
europepmc +1 more source
Characterization of a mosquitocidal botulinum toxin-like neurotoxin complex
reservedParaclostridial mosquitocidal protein 1 (PMP1), a botulinum-like toxin from Paraclostridium bifermentans, belongs to the clostridial neurotoxin (CNT) family, which includes botulinum and tetanus neurotoxins.
ANTONELLO, MARTA
core
A Case Report of Herpes Zoster After Botulinum Toxin Injections [PDF]
Shadi Zari Department of Dermatology, College of Medicine, University of Jeddah, Jeddah, Saudi ArabiaCorrespondence: Shadi Zari, Department of Dermatology, College of Medicine, University of Jeddah, Saudi Arabia, Email Shadizarimd@gmail.comAbstract: This
Zari S
core
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond +6 more
wiley +1 more source