Results 201 to 210 of about 19,548 (244)
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Glycosphingolipids—Sweets for botulinum neurotoxin
Glycoconjugate Journal, 2004A number of viruses, bacteria, and bacterial toxins can only act on cells that express the appropriate glycosphingolipids (GSLs) on the outer surface of their plasma membranes. An example of this dependency is provided by botulinum neurotoxin (BoNT) which is synthesized by Clostridium botulinum and inhibits neurotransmission at the neuromuscular ...
Brian C, Yowler, Cara-Lynne, Schengrund
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Uptake of Botulinum Neurotoxin in the Intestine
2012Foodborne and intestinal botulism are the most common forms of human botulism; both result from the absorption of botulinum neurotoxin (BoNT) from the digestive tract into the circulation. BoNT is a large protein toxin (approximately 150 kDa), but it is able to pass through the epithelial barrier in the digestive tract.
Yukako, Fujinaga +2 more
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Revue neurologique, 2010
Botulinum toxin is a multi-molecular complex comprised of a neuro-active moiety (i.e. botulinum neurotoxin) and several associated non-toxic proteins. The toxin dissociates rapidly at plasmatic pH, thereby releasing neurotoxin. Nerve terminals only take up the neurotoxin.
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Botulinum toxin is a multi-molecular complex comprised of a neuro-active moiety (i.e. botulinum neurotoxin) and several associated non-toxic proteins. The toxin dissociates rapidly at plasmatic pH, thereby releasing neurotoxin. Nerve terminals only take up the neurotoxin.
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Pharmacology of Botulinum Neurotoxin Serotype A
American Journal of Health-System Pharmacy, 2004An historical perspective on the discovery and development of botulinum neurotoxin for commercial use, the differences between various botulinum toxin serotypes and commercially available products, and the structure, mechanism of action, pharmacologic effects, and immunogenicity of botulinum toxin type A are discussed.Botulinum toxin was discovered ...
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Complications of Botulinum Neurotoxin
Disease-a-Month, 2009Dave W, Lu, Jonathan, Lippitz
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Botulinum neurotoxin ในทางการแพทย์ ;Medical appication of Botulinum neurotoxin
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[Clostridium botulinum and botulinum neurotoxin].
Brain and nerve = Shinkei kenkyu no shinpo, 2011Clostridium botulinum is a gram-positive anaerobic rod that forms endospores. This bacterium produces large molecular toxin complexes, namely botulinum toxin complexes (progenitor toxins). It (L toxin complex) is composed of a single neurotoxin molecule (BoNT with a molecular weight of 150 kDa), a single nontoxic nonhemagglutinin molecule (NTNHA), and ...
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