Results 151 to 160 of about 18,120 (266)

Botulinum toxin type A versus botulinum toxin type B for cervical dystonia

, 2016
Background This is an update of a Cochrane review first published in 2003, and previously updated in 2009 (no change in conclusions). Cervical dystonia is the most common form of focal dystonia and is a disabling disorder characterized by painful involuntary head posturing.
openaire   +1 more source

Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim, Fatima Al Sarraf, Hana Cho, Navdeep Kumar   +3 more
wiley   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Real‐World Patient Characteristics and Treatment Patterns Among Patients With Interstitial Cystitis (IC)/Bladder Pain Syndrome (BPS)

Reproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Objective Interstitial cystitis/bladder pain syndrome (IC/BPS) is linked to bladder and/or pelvic pain, pressure, and discomfort with urinary frequency. Despite guidelines, there is a need for better treatment options. This study analyzed patient demographics, clinical characteristics, and treatment patterns for medications and procedures in ...
Jaromir Mikl, Tiange Yu, Benjamin T. Carter, Andrew Rava, Xin Zhao, Catherine Allende, Amie Devlin, Valentine Pascale, Roger Dmochowski   +8 more
wiley   +1 more source

Emerging Treatments for Erectile Dysfunction

Trends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Erectile dysfunction (ED) is a prevalent condition that can significantly affect men's sexual health and quality of life, and for which there are many well‐studied effective treatments. In spite of this, many individuals still seek out alternative therapies.
Resa Magill, Jeff Morrison, Juan Andino, Jasper Bash   +3 more
wiley   +1 more source

Phenol Neurolysis in Pain and Palliative Medicine

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers, Rachel J. H. Smits, Alopi M. Patel, Robert T. M. van Dongen, Cornelis K. Kramers, Jacqueline M. Bos, Selina E. I. van der Wal   +6 more
wiley   +1 more source

Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia

Annals of Neurology, Volume 99, Issue 5, Page 1227-1238, May 2026.
Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani, Shiro Horisawa, Konstantin Butenko, Hiroki Togo, Arun Garimella, William Drew, Melissa Chua, Esraa Shaban, Takakazu Kawamata, Takaomi Taira, Andreas Horn, Michael D. Fox, Takashi Hanakawa   +12 more
wiley   +1 more source

Botulinum toxin type A in pregnancy.

Canadian family physician Medecin de famille canadien, 2014
My patient received 62 units of botulinum toxin type A (BTX-A) for facial lines. Two weeks later, she found out that she was pregnant. Will this cause any harm to her fetus?Botulinum toxin is not expected to be present in systemic circulation following proper intramuscular or intradermal injection.
Michael, Tan, Eunji, Kim, Gideon, Koren, Pina, Bozzo   +3 more
openaire   +1 more source

Acute Respiratory Failure From Massive Esophageal Dilatation due to Achalasia

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Massive esophageal dilatation secondary to achalasia resulting in acute hypoxic respiratory failure from cardiopulmonary mass effect. ABSTRACT Massive esophageal dilation from achalasia can cause acute respiratory failure via lung compression. Prompt recognition and urgent esophageal decompression can rapidly reverse hypoxia and be lifesaving.
Frank Epitropoulos, Omar Brijawi, Sumit Sharma   +2 more
wiley   +1 more source

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley, Joshua D. Bryant, Samuel Vrana, Karuppiah Chockalingam, Zhilei Chen   +4 more
wiley   +1 more source