Results 131 to 140 of about 120,548,321 (260)

The Effects of OnabotulinumtoxinA Treatment for Spasticity in Patients With Spinal Cord Injury: A Systematic Review and Meta-analysis [PDF]

open access: yesعلوم بهداشتی ایران
Background and Purpose: Spasticity is a disabling complication of spinal cord injury (SCI). The administration of various medications is not satisfactory. Studies show the effects of onabotulinumtoxinA treatment for spasticity in patients with SCI.
Maryam Hosseini   +6 more
doaj  

Temporal Associations Between Physiological Sleep and Next‐Day Pain Intensity in Individuals With Activity‐Limiting Chronic Pain: A Multiple Night At‐Home Ear‐EEG Sleep‐Monitoring Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Chronic pain and sleep disturbances frequently co‐occur. However, most prior research relies on self‐report or actigraphy, which reflect behavioural aspects of sleep but provide only limited insight into the underlying sleep physiology. In this pre‐registered prospective observational study (NCT06368531), we investigated within‐person night‐to‐
Henrik Bjarke Vaegter   +7 more
wiley   +1 more source

Botulinum toxin type A in the treatment of patients with cervical dystonia

open access: yes, 2008
Allison BrashearDept of Neurology, Wake Forest University Baptist, Medical Center, Winston Salem, NC, USAAbstract: Dystonia is an involuntary movement involving twisting and turning of agonist and antagonist muscles. Cervical dystonia is isolated to neck
Allison Brashear
core  

Gastrocnemius muscle properties in children with cerebral palsy: An exploratory cross‐sectional study of variability in gastrocnemius properties

open access: yesExperimental Physiology, EarlyView.
Abstract Muscle strength is a key predictor of physical functioning, yet the influence of patient and treatment factors on muscle properties in young people with cerebral palsy is not fully known. We explored whether medial gastrocnemius properties vary by age, ambulatory status and spasticity treatment (botulinum toxin or selective dorsal rhizotomy ...
Elizabeth R. Boyer   +7 more
wiley   +1 more source

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source

Therapeutic Strategies for a Narrative Review With Emphasis on Intravesical, Procedural and Regenerative Approaches Bladder Pain Syndrome

open access: yesTrends in Urology &Men's Health, Volume 17, Issue 6, December 2026.
ABSTRACT Bladder pain syndrome (BPS) is a chronic, heterogeneous condition impair patients' quality of life. expanding body of clinical evidence clinical decision‐making is by variability in patient phenotypes, endpoints, and follow‐up. significantlyingWhilst there is anin relation to potential treatment options, often hindered study inconsistencies ...
Zhila Sheikhi   +4 more
wiley   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

open access: yesJournal of Cutaneous Pathology, Volume 53, Issue 12, Page 1165-1171, December 2026.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond   +6 more
wiley   +1 more source

Passive shoulder mobility and active shoulder external rotation recovery in upper‐trunk brachial plexus birth injuries after nerve repair

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 12, Page 1712-1719, December 2026.
This was a retrospective cohort study of 322 patients with upper trunk brachial plexus birth injury following nerve surgery of C5 and/or C6. We found that a substantial gap remained between passive and active shoulder external rotation in adduction, indicating that passive mobility is not the limiting factor in active external rotation recovery ...
Eva T. E. Ulmann   +3 more
wiley   +1 more source

Classification of Complex Regional Pain Syndrome Patients Using Neuropathic Pain Symptoms—A Secondary, Retrospective Analysis From ncRNAPain

open access: yesEuropean Journal of Pain, Volume 30, Issue 10, November 2026.
ABSTRACT Background Complex Regional Pain Syndrome (CRPS) is a rare chronic pain disorder characterized by a heterogeneous symptom profile, including severe pain, allodynia and motor dysfunction. In previous work, we demonstrated elevated levels of neuropathic pain symptoms in CRPS, suggesting that refined symptom‐based stratification may improve ...
Bruno Rogalla von Bieberstein   +5 more
wiley   +1 more source

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