Results 121 to 130 of about 18,120 (266)

Botulinum toxin use in patients with neurological disorders: A U.S.‐based claims database analysis

PM&R, EarlyView.
Abstract Background and Objective Real‐world evidence describing long‐term persistency with botulinum toxin (BoNT) therapy is limited. We assessed treatment patterns and persistency with BoNT in clinical practice over 2 years. Design Retrospective, longitudinal, claims database analysis. Setting Medical claims data from the Merative MarketScan database
David M. Simpson, Jonathan Bouchard, Simon Page, Seth Goldfarb, Atul T. Patel   +4 more
wiley   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest
Lin‐Lin Lan, Qiu‐Rong Yang, Pei‐Yun Zhuang   +2 more
wiley   +1 more source

The Effects of OnabotulinumtoxinA Treatment for Spasticity in Patients With Spinal Cord Injury: A Systematic Review and Meta-analysis [PDF]

علوم بهداشتی ایران
Background and Purpose: Spasticity is a disabling complication of spinal cord injury (SCI). The administration of various medications is not satisfactory. Studies show the effects of onabotulinumtoxinA treatment for spasticity in patients with SCI.
Maryam Hosseini, Saeed Vaheb, Mohaddeseh Azadvari, Mohsen Rastkar, Mahsa Ghajarzadeh, Maryam Cheraghali, Seyede Zahra Emami Razavi   +6 more
doaj  

Radiological Findings Post Autologous Fat Grafting and Breasts Procedures: Avoiding False Positive Results

ANZ Journal of Surgery, EarlyView.
This article highlights the importance of understanding the imaging features and complications of fat necrosis and oil cysts to improve diagnostic accuracy and clinical management. A rational diagnostic sequence—emphasizing comparison with prior imaging, careful evaluation of morphological changes, and judicious use of biopsy—can reduce unnecessary ...
Eduardo de Faria Castro Fleury
wiley   +1 more source

Tale of Two Centres—Exploring Bedside Challenges to Implementing a Clinical Quality Registry for Abdominal Wall Hernias in Metropolitan Australia

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background In an effort to improve hernia care and mesh product surveillance, the Australia and New Zealand Hernia Society (ANZ Hernia) has been setting up a prototype binational learning healthcare system virtual clinical quality registry (CQR) for clinical use.
Edward Young, Doug Fenton‐Lee, Julian Süsstrunk, Jorgen Ferguson, Matthew Amprayil, Yijie Yin, Rabieh Abu Assi, Alex Karatassas, Sanjeev Khurana, Chrys Hensman, Andrew Tse, Hamish Urquhart, Reginald V. N. Lord, Jean Wong, Darren Tonkin, Markus Trochsler, Guy J. Maddern   +16 more
wiley   +1 more source

Use of botulinum toxin as a preoperative adjuvant in incisional hernia repair performed using the Rives-Stoppa technique in a pediatric patient: a case report

Revista de la Facultad de Medicina
Introduction. Although incisional hernia is a rare condition in pediatric patients, it is relevant because of its possible complications and esthetic and functional impact. Case presentation.
Paula Andrea Quintero-Garzón, Jose Ricardo Torres-Pulido, Fernando Augusto Escobar   +2 more
doaj   +1 more source

Altered cytoskeletal integrity underlies impaired platelet shape change and defective thrombus formation in ETV6‐related thrombocytopenia

British Journal of Haematology, EarlyView.
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov, Julia‐Jessica D. Korobkin, Daria V. Fedorova, Sofia V. Galkina, Maria M. Golomysova, Sergei I. Obydennyi, Anastasia A. Ignatova, Ekaterina‐Iva A. Adamanskaya, Eugenia V. Yushkova, Anna V. Pavlova, Pavel A. Zharkov, Igor I. Kireev, Galina A. Novichkova, Viktor G. Zgoda, Mikhail A. Panteleev, Anastasia N. Sveshnikova   +15 more
wiley   +1 more source

Long-term response of different Botulinum toxins in refractory neurogenic detrusor overactivity due to spinal cord injury

International Brazilian Journal of Urology
Purpose To assess the response in spinal cord injured patients alternatively treated with different types and dosages of Botulinum neurotoxin type A (BoNT/A) over 15 years.
Giuseppe Lombardi, Stefania Musco, Giovanni Bacci, Maria Celso, Valerio Bellio, Giulio Del Popolo   +5 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source