Results 101 to 110 of about 120,548,321 (260)

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

Botulinum toxin type-A in the treatment of glabellar lines

, 2009
Leslie Winter1, Jeffrey Spiegel21Department of Otolaryngology, Boston Medical Center, Boston, MA, USA; 2Chief, Division of Facial Plastic Surgery Boston Medical Center Boston, MA, USAAbstract: The current literature and state of the art on use of ...
Leslie Winter, Jeffrey Spiegel
core  

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest
Lin‐Lin Lan, Qiu‐Rong Yang, Pei‐Yun Zhuang   +2 more
wiley   +1 more source

Capsaicin protects neuromuscular junctions from the inhibitory effects of botulinum neurotoxin A [PDF]

, 2008
Within 24 hrs after injecting botulinum neurotoxin A (BoNT/A) into the hindlimb, mice lost the toe spread reflex and developed progressive muscle weakness. At the same time, the compound muscle action potential amplitude decreased. Injection of capsaicin
Carmen Garcia, Joseph McArdle, Kormakur Hognason, Joseph Potian, Baskaran Thyagarajan, Natalia Krivitskaya   +5 more
core  

Incidences of Mould and Bacterial Toxins in Dairy Products

, 2016
This chapter reviews the common bacterial toxins and mycotoxins involved in food poisoning in milk and dairy products. Food-borne bacterial infection occurs when food contaminated with pathogenic bacteria is consumed. The major type of diseases caused by
El-Nezamy, HS, Wan, MLY, N.P. Shah, M.L.Y. Wan, H.I. El-Nezami, Shah, NP   +5 more
core   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Outcomes of Long‐Term Absorbable Mesh Use for Ventral Hernia Repair in Immunosuppressed Patients

World Journal of Surgery, EarlyView.
Immunosuppressed patients are more at risk of perioperative infections. In case of ventral hernia repair, the use of a long‐term absorbable mesh could potentially decrease the infectious risk in these patients. This study aimed to assess the short‐ and mid‐term outcomes of ventral hernia repair with long‐term absorbable mesh in immunosuppressed and non‐
Gaëtan‐Romain Joliat, Benoit Romain, Guillaume Passot   +2 more
wiley   +1 more source

Real-World Safety And Effectiveness Of OnabotulinumtoxinA Treatment Of Crow’s Feet Lines And Glabellar Lines: Results Of A Korean Postmarketing Surveillance Study

Clinical, Cosmetic and Investigational Dermatology, 2019
Dong-Jin Yi,1 Seongjin Hwang,2 JunHyuk Son,3 Irina Yushmanova,4 Krystal Anson Spenta,5 Suzanne St.Rose6 1BLS Clinic, Seoul, Republic of Korea; 2Fulore Clinic, Seoul, Republic of Korea; 3Department of Ophthalmology, Yeungnam University College of Medicine,
Yi DJ, Hwang S, Son J, Yushmanova I, Anson Spenta K, St.Rose S   +5 more
doaj  

Pathophysiology of Delayed Gastric Conduit Emptying After Oesophagectomy: A Multicentre Cohort Study

ANZ Journal of Surgery, EarlyView.
In this multicentre study of 272 patients, early and late delayed gastric conduit emptying after oesophagectomy emerged as distinct phenotypes. Early DGCE was predicted by open surgery, whereas late DGCE was predicted by GOJ tumour location and postoperative complications.
Jonathan Sivakumar, Erica Lim, Shaun Chew, Lynn Chong, Qianyu Chen, Michael W. Hii, Cuong P. Duong, Salena Ward, Matthew Read, David S. Liu, Mary Ann Johnson   +10 more
wiley   +1 more source