Results 101 to 110 of about 18,120 (266)

Iatrogenic Botulism After Botulinum Toxin Type A Injections

Clinical Neuropharmacology, 2010
Therapeutic use of botulinum toxin type A (BT/A) is well known, effective, and safe. Iatrogenic botulism that presents with generalized weakness, dysphagia, and respiratory distress is a rare but significant complication in BT/A treatment. In this study, we report 4 patients who developed iatrogenic botulism after receiving therapeutic doses of BT/A ...
Çoban, Arzu, Matur, Zeliha, Hanağası, Haşmet Ayhan, Parman, Yeşim Gülşen   +3 more
openaire   +3 more sources

Clinical Outcome Assessments for Functional Performance in Spastic Paresis: Systematic Review, Critique, and Recommendations

Movement Disorders, EarlyView.
Abstract Background Spastic paresis, resulting from central nervous system lesions, significantly impairs functional performance. In the framework of the International Classification of Functioning, Disability, and Health, functional performance was defined as functioning at the activity level in relation to the impairment of body functions and ...
Martina Hoskovcova, Marjolaine Baude, Bo Biering‐Sørensen, Ota Gal, Mary P Galea, Jean‐Michel Gracies, Carmen Rodriguez‐Blazquez, Theodore Wein, Michelle Hyczy de Siqueira Tosin, Álvaro Sánchez‐Ferro, Tiago A Mestre, Matej Skorvanek, Robert Jech, The members of the MDS Clinical Outcome Assessments Scientific Evaluation Committee and MDS Spasticity Study Group   +13 more
wiley   +1 more source

Real-World Safety And Effectiveness Of OnabotulinumtoxinA Treatment Of Crow’s Feet Lines And Glabellar Lines: Results Of A Korean Postmarketing Surveillance Study

Clinical, Cosmetic and Investigational Dermatology, 2019
Dong-Jin Yi,1 Seongjin Hwang,2 JunHyuk Son,3 Irina Yushmanova,4 Krystal Anson Spenta,5 Suzanne St.Rose6 1BLS Clinic, Seoul, Republic of Korea; 2Fulore Clinic, Seoul, Republic of Korea; 3Department of Ophthalmology, Yeungnam University College of Medicine,
Yi DJ, Hwang S, Son J, Yushmanova I, Anson Spenta K, St.Rose S   +5 more
doaj  

Phenotyping Overactive Bladder – Part 2: Can Management be Improved by Phenotyping, and Targeting Therapy According to Urgency Type and Other Characteristics? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Management of overactive bladder (OAB) has a stepwise approach in adults and children. This does not account for individual patient variations, which may explain suboptimal outcomes in many patients. Distinct OAB profiles, based on patient characteristics, symptoms, urodynamic findings and imaging have been discussed in Part 1 ...
Michel Wyndaele, Michael Samarinas, Apostolos Apostolidis, D. Carolina Ochoa, Giovanni Mosiello, Brigitte Schurch, Pradeep Tyagi, Alan Wein, Paul Abrams, John E. Speich   +9 more
wiley   +1 more source

Widespread Sequence Variations in VAMP1 across Vertebrates Suggest a Potential Selective Pressure from Botulinum Neurotoxins [PDF]

, 2014
Botulinum neurotoxins (BoNT/A-G), the most potent toxins known, act by cleaving three SNARE proteins required for synaptic vesicle exocytosis. Previous studies on BoNTs have generally utilized the major SNARE homologues expressed in brain (VAMP2 ...
Adler, Michael, Borrell, Andrew, Demogines, Ann, Dong, Min, Johnson, Eric A., Liu, Huisheng, Peng, Lisheng, Sawyer, Sara L., Tao, Liang, Tepp, William H., Zhang, Su-Chun   +10 more
core   +3 more sources

Should We Consider Sacral Nerve Stimulation as a Treatment for Neurogenic Lower Urinary Tract Dysfunction? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To explore the boundary of clinical use of sacral nerve stimulation (SNS) in neurogenic lower urinary tract dysfunction (NLUTD), identifying barriers to approval and early‐impact research questions. Methods This review is derived from a proposal discussion at the International Consultation on Incontinence‐Research Society in Bristol in ...
Marcus J. Drake, Mathijs de Rijk, Stefania Musco, Jalesh Panicker, Michał Późniak, Nikita Bhatt, Brigitte Schurch   +6 more
wiley   +1 more source

Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]

, 1994
The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Binz, T., Dayanithi, G., Gratzl, Manfred, Höhne-Zell, B., Niemann, H., Stecher, B., Weller, U., Yamasaki, S.   +7 more
core   +1 more source

Pneumothorax after botulinum toxin type A

Annals of Physical and Rehabilitation Medicine, 2012
literature. Case report.– A 27-year-old patient, with PKAN heredodegenerative dystonia, has truncal dystonia symptomatology. Suddenly, she complained of low-back pain evaluated at 10/10 on a verbal scale. Low-back pain is induced by repetitive dystonic movements with upper limbs anterior elevation, spinal and hip extension (opisthotonos).
Dongas, A., Genet, F., Popoff, M., Faye, M., Jourdan, C., Schnitzler, A.   +5 more
openaire   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk, Michel Wyndaele, Ana Charrua, Christopher Fry, Paul Abrams, Gommert A. van Koeveringe, Anthony J. Kanai, Marcus J. Drake   +7 more
wiley   +1 more source

Recombinant synthesis and immunological characterization of single-domain antibodies against botulinum neurotoxin serotype A and B

Tạp chí Kiểm nghiệm và An toàn thực phẩm
Nanobodies which are single-domain antibodies derived from the Variable Heavy domain of Heavy-chain-only antibodies (VHHs) found in camels and sharks, represent a novel approach for enhancing the detection and neutralization of food toxins.
Luong Trung Hieu, Bui Thi Thu Hoai, Phan Thi Thanh Thuy, Nguyen Le Duc Hai, Nguyen Thi Anh Nguyet, Pham Bao Yen, Nguyen Thi Hong Loan, Phan Tuan Nghia, Nguyen Thanh Trung, Le Phuong Linh, Trinh Van Toan, Le Thi Hong Nhung   +11 more
doaj   +1 more source