Results 111 to 120 of about 18,120 (266)

Botulinum toxin type B for cervical dystonia [PDF]

, 2016
BACKGROUND: This is an update of a Cochrane review first published in 2004, and previously updated in 2009 (no change in conclusions). Cervical dystonia is a frequent and disabling disorder characterised by painful involuntary head posturing.
Castelão, M, Costa, J, Duarte, GS, Ferreira, J, Marques, RE, Moore, AP, Rodrigues, FB, Sampaio, C   +7 more
core   +1 more source

Phenotyping Overactive Bladder—Part 1: Are There Different Types of Urgency and Can They be Translated to Clinical, Urodynamic and Radiological Phenotyping? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Overactive bladder (OAB) is defined as urinary urgency, usually accompanied by increased daytime frequency and/or nocturia, with urgency urinary incontinence (OAB‐wet) or without (OAB‐dry), in the absence of urinary tract infection or other detectable disease.
John E. Speich, D. Carolina Ochoa, Pradeep Tyagi, Apostolos Apostolidis, Sanjay Sinha, Claire Hentzen, Marcus Drake, Paul Abrams, Alan J. Wein, Michel Wyndaele   +9 more
wiley   +1 more source

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan, Alyssa Kobayashi, Zhina Sadeghi   +2 more
wiley   +1 more source

Can the positions of the spastic upper limb in stroke survivors help muscle choice for botulinum toxin injections?

Arquivos de Neuro-Psiquiatria
Motor impairments in stroke survivors are prevalent and contribute to dependence in daily activities, pain and overall disability, which can further upper-limb disability.
André Luiz Salcedo Gomes, Francisco Falleiros de Mello, Jorge Cocicov Neto, Marcelo Causin Benedeti, Luis Felipe Miras Modolo, Marcelo Riberto   +5 more
doaj   +1 more source

Phospholipase C Produced by Clostridium botulinum Types C and D:Comparison of Gene, Enzymatic, and Biological Activities with Those of Clostridium perfringens Alpha-toxin [PDF]

, 2013
Clostridium botulinum type C and D strains recently have been found to produce PLC on egg yolk agar plates. To characterize the gene, enzymatic and biological activities of C.
Fatmawati, Ni Nengah Dwi, Matsushita, Osamu, Oda, Masataka, Oguma, Keiji, Sakaguchi, Yoshihiko, Sakurai, Jun, Shimizu, Kenta, Suzuki, Tomonori, Yamamoto, Yumiko   +8 more
core   +1 more source

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

Fragment C of Tetanus Toxin : New Insights into Its Neuronal Signaling Pathway [PDF]

, 2012
When Clostridium tetani was discovered and identified as a Gram-positive anaerobic bacterium of the genus Clostridium, the possibility of turning its toxin into a valuable biological carrier to ameliorate neurodegenerative processes was inconceivable ...
Acheson, Aguilera, Ana C. Calvo, Anderson, Barati, Boquet, Borasio, Bordet, Brooks, Calappi, Carlton, Chaib-Oukadour, Chaib-Oukadour, Check, Chen, Chen, Ciriza, Coen, Conway, Cosman, Cowie, Deinhardt, Deinhardt, Deinhardt, Emsley, Evinger, Firor, Fishman, Flexner, Fotinou, Gil, Gil, Gil, Gil, Habermann, Habermann, Harvey, Helting, Herreros, Herreros, Humeau, Inserte, Ipsen, Jayaraman, Jayaraman, Johnson, Johnson, Johnson, José Aguilera, Lalli, Landsteiner, Larsen, Lazarovici, Louch, Manning, Manwaring, Martini, Mendieta, Menestrina, Miana-Mena, Miana-Mena, Miana-Mena, Mochida, Montal, Moreno-Igoa, Moreno-Igoa, Neubauer, Noguchi, Oliveira, Pelliccioni, Pellizari, Pilar Zaragoza, Raquel Manzano, Roaf, Rosario Osta, Roux, Rummel, Sara Oliván, Sherrington, Siade, Simpson, Sinha, Skaper, Skeldal, Sugiyama, Sutton, Thorne, Twiss, Ungar, Van Heyningen, Van Heyningen, Van Heyningen, Van Heyningen, Wang, Wassermann, Wright   +95 more
core   +3 more sources

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, EarlyView.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source

A Comprehensive Review of the Genetic Etiology and Management of Orofacial Clefts

Pediatric Discovery, EarlyView.
ABSTRACT Cleft lip (CL) and cleft palate (CP), collectively referred to as orofacial clefts (OFCs), are among the most common birth defects and can have significant effects on speech, nutrition, and physical and psychosocial development. Manifestation, classification, and treatment plans of OFCs are diverse and not standardized.
Emily Kim, Rebeka Dejenie, Caroline Kim, Russell Reid   +3 more
wiley   +1 more source

Expanding the Phenotype of PARK‐PRKN to Spastic Paraplegia: A Report of Two Cases

Movement Disorders Clinical Practice, EarlyView.
Nicolas Geoffre, Thomas Ollivier, Guillaume Baille, Luc Defebvre, Vincent Huin, Eugenie Mutez   +5 more
wiley   +1 more source