Results 81 to 90 of about 120,548,321 (260)

Surgical Indications for Type II Thyroplasty in Adductor Spasmodic Dysphonia: A Scoping Review

The Laryngoscope, EarlyView.
This scoping review mapped evidence on surgical eligibility, efficacy, durability, and safety of Type II thyroplasty with titanium bridges for adductor spasmodic dysphonia and proposed preliminary international surgical indication criteria and a core outcome set.
Marice Sangalang, Tetsuji Sanuki, Ahmed Geneid, Yakubu Karagama, Nobuhiko Oridate   +4 more
wiley   +1 more source

Botulinum toxin for submandibular gland treatment: A scoping review of aesthetic and functional outcomes [PDF]

Surgical & Cosmetic Dermatology
Enlarged or ptotic submandibular glands (SmG) can negatively impact the mandibular angle and facial contour. Although botulinum toxin type A (BoNT-A) is well established as a treatment for parotid hypertrophy, its use for the treatment of SmG enlargement
Doris Hexsel, Clarissa Reinehr, Patricia Caspary, Gabriela Mosena, Vitor Costa Fabris   +4 more
doaj   +1 more source

From Disability to Diagnosis: Baseline Findings from the Calgary Functional Movement Disorder Registry

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Functional movement disorder (FMD), a subtype of functional neurological disorder, is a complex neuropsychiatric syndrome characterized by inconsistent and incongruent motor symptoms. Despite its relatively high prevalence, FMD remains associated with delayed diagnosis, significant disability, and limited evidence to guide ...
Andrea Soumbasis, Brian Steele, Megan Howlett, Kate Kain, Davide Martino, Kimberly G. Williams, Gabriela S. Gilmour   +6 more
wiley   +1 more source

Recombinant versus native botulinum neurotoxin type A: structural and pharmacodynamic comparison. [PDF]

Acta Crystallogr F Struct Biol Commun
For the first time, the recombinant core botulinum neurotoxin type A (BoNT/A) expressed in Escherichia coli and nicked in vitro is shown to be structurally identical to native BoNT/A from Clostridium botulinum, enabling direct activity comparison between the recombinant product and the native toxin.Botulinum neurotoxins (BoNTs) are highly potent ...
Yao Z, Xu L, Lu Y, Gong H, Sun X, Zhao Y, Chen J, Yang L, Chen Q, Yang W.   +9 more
europepmc   +2 more sources

Efficacy of IncobotulinumtoxinA (BoNT‐A) Injections in Upper Limb Task‐Specific and Position‐Dependent Tremors

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Task‐specific tremors (TST) and position‐dependent tremors (PDT) are rare isolated focal tremors that impair fine motor control with few effective treatment options. Although botulinum neurotoxin (BoNT) is effective in other tremor syndromes, its evidence in these tremor subtypes remains limited.
Elizabeth K. Boyd, Shangge Jiang, Runjie Bill Shi, Philippe Rizek   +3 more
wiley   +1 more source

Kinematic Features of Voluntary and Involuntary Head Movements in Cervical Dystonia

Movement Disorders, EarlyView.
Abstract Background Cervical dystonia (CD) has a varied motor presentation, combining abnormal postures with complex involuntary head movements. Classification of these motor patterns remains imprecise, relying on descriptive terminology without robust definitions. Objectives To provide a kinematically‐grounded description of the motor phenomenology of
Thomas Hart, Davide Martino, Larissa R. Heideman, Martijn Beudel, Mark J. Edwards, Anna Sadnicka, Francesca Morgante   +6 more
wiley   +1 more source

Bacterial Toxins: Friends or Foes?

Emerging Infectious Diseases, 1999
Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes.
Clare K. Schmitt, Karen C. Meysick, Alison D. O'Brien   +2 more
doaj   +1 more source

Characterisation of botulinum toxins type A and B, by matrix-assisted laser desorption ionisation and electrospray mass spectrometry

, 2002
A method earlier developed for the mass spectrometric (MS) identification of tetanus toxin (TTx) was applied to botulinum toxins type A and B (BTxA and BTxB).
Baar, B.L.M. van, Jong, A.L. de, Hulst, A.G., Wils, E.R.J.   +3 more
core  

The Benefits of Adding Non‐Antimuscarinic Pharmaceuticals in Combination With Beta‐3 Agonists for Overactive Bladder Treatment: A Systematic Review

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith, Charlotte Phelps, Christian Moro   +2 more
wiley   +1 more source

Entering neurons: botulinum toxins and synaptic vesicle recycling. [PDF]

, 2006
Botulinum toxins are metalloproteases that act inside nerve terminals and block neurotransmitter release through their cleavage of components of the exocytosis machinery.
Matteoli M, Frassoni C, Montecucco C, Verderio C, Grumelli C, Rossetto O   +5 more
core   +2 more sources