Results 211 to 220 of about 120,548,321 (260)

Clinical use of non-a botulinum toxins: botulinum toxin type B

Neurotoxicity Research, 2006
Botulinum neurotoxin type B (BT, BT-B) has been used as NeuroBloc/MyoBloc since 1999 for treatment of cervical dystonia, hyperhidrosis, spastic conditions, cerebral palsy, hemifacial spasm, bladder dysfunction, spasmodic dysphonia, sialorrhoea, anal fissures, piriformis syndrome, various pain conditions and cosmetic applications.
D, Dressler, R, Eleopra
openaire   +2 more sources

Botulinum Toxin Type B

Dermatologic Surgery, 2003
Botulinum toxin B is an antigenically distinct form of Botulinum toxin which has unique physical and clinical properties that distinguish it from Botulinum toxin A.To describe properties of Botulinum toxin B.More rapid onset, greater diffusion characteristics as well as diminished longevity have been identified to date in previous studies.BTX-B is safe
openaire   +2 more sources

Botulinum Toxin Type B for Dynamic Glabellar Rhytides Refractory to Botulinum Toxin Type A

Dermatologic Surgery, 2003
Botulinum toxin type B (BTX-B; Myobloc) has recently been introduced for the treatment of dynamic rhytides. This serotype is structurally similar to botulinum toxin type A (BTX-A; Botox) and appears to produce equivalent muscular paralysis. Because of the fact that some patients may become resistant to the effects of BTX-A with its continued use or may
Tina S, Alster, Jason R, Lupton
openaire   +2 more sources

Botulinum toxin type B in antibody-induced botulinum toxin type A therapy failure

Journal of Neurology, 2003
Recently, it was reported that botulinum toxin type B complex (BoNT/B) (NeuroBloc(R), Elan Pharmaceuticals) can produce an adequate therapeutic response in patients with antibody induced failure of botulinum toxin type A complex (BoNT/A) therapy. We wanted to study whether this effect is transient or sustained.
Dirk, Dressler, Hans, Bigalke, Reiner, Benecke   +2 more
openaire   +2 more sources

Different types of botulinum toxin in humans

Movement Disorders, 2004
In humans, botulinum neurotoxin (BoNT) serotype A (BoNT/A) is a useful therapeutic tool, but different BoNT serotypes may be useful when a specific immune resistance related to BoNT/A is proved. BoNT serotype F (BoNT/F) was injected into human muscles but its effects are shorter compared to BoNT/A, whereas BoNT serotype B (BoNT/B) is effective in ...
ELEOPRA R, TUGNOLI V, QUATRALE R, ROSSETTO, ORNELLA, MONTECUCCO, CESARE   +4 more
openaire   +2 more sources

Purification of Clostridium botulinum type a toxin

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1970
Abstract The neurotoxin of Clostridium botulinum Type A has been isolated and purified from a liquid culture. The toxin is homogeneuous by anion and cation exchange chromatography, gel filtration, isoelectric focusing and Ouchterlony gel diffusion technique. The specific toxicity of the purified toxin is 10 · 107 minimum lethal doses/1.0 A 278
B R, Dasgupta, L J, Berry, D A, Boroff
openaire   +2 more sources

Detoxification of Crystalline Botulinum Type A Toxin

The Journal of Immunology, 1947
Summary Botulinum Type A toxoid has been prepared from crystalline toxin by the addition of formaldehyde. The most active preparation consisted of one component electrophoretically, immunized mice in a dose containing 0.01γ of toxoidnitrogen and was 2400 times more active antigenically than crude toxoid on the basis of nitrogen-content.
G A, HOTTLE, A, ABRAMS
openaire   +2 more sources

Botulinum toxin type A in chronic migraine

Expert Review of Neurotherapeutics, 2007
The use of botulinum toxin type A continues to be investigated by the US FDA for potential use in the treatment of headache. As part of this process there has been extensive research conducted by individual study sites as well as multicenter trials. To date, the majority of the focus has been on migraine headache as well as on tension-type headache ...
openaire   +2 more sources

Botulinum Toxin Type A for Chronic Migraine

Current Neurology and Neuroscience Reports, 2010
Chronic migraine (CM) is the leading cause of chronic daily headache, a common and debilitating headache syndrome. The management of CM patients is challenging, with only limited benefit from available oral preventive medications. Botulinum neurotoxin (BoNT) has been used extensively to treat disorders associated with increased muscle tone. More recent
openaire   +2 more sources

Molecular Weight of Type A Botulinum Toxin

Infection and Immunity, 1970
Clostridium botulinum type A does not produce a 12,000 molecular weight toxin. The reported isolation of such a material by Gerwing et al. could not be confirmed.
J N, Knox, W P, Brown, L, Spero
openaire   +2 more sources