Results 171 to 180 of about 119,004 (251)

Advancing Personalized Care for Neurogenic Bladder: The Case for Continent Urinary Diversion

Neurourology and Urodynamics, Volume 45, Issue 8, Page 1489-1492, November 2026.
ABSTRACT Introduction Neurogenic lower urinary tract dysfunction (NLUTD) with a poorly compliant bladder that is refractory to minimally invasive therapies (MIT) represents an “end‐stage” phenotype in which the principal objectives are durable upper urinary tract protection and restoration of continence with acceptable long‐term morbidity.
Francis A. Jefferson, Maude E. Carmel
wiley   +1 more source

Urodynamic Voiding Patterns in Multiple Sclerosis

Neurourology and Urodynamics, Volume 45, Issue 8, Page 1569-1577, November 2026.
ABSTRACT Aims This study aimed to describe urodynamic voiding patterns in patients with MS (PwMS) using standardized assessments, and to compare the performance of the available nomograms and indices for obstruction and bladder contractility. Methods PwMS and lower urinary tract symptoms underwent cystometry and pressure flow studies.
Camille Chesnel, Nicolas Turmel, Maelys Teng, Emilie Blouet, Gérard Amarenco, Claire Hentzen   +5 more
wiley   +1 more source

Botulinum toxins in clinical practice: Gaps in knowledge. [PDF]

Neurol Clin Pract, 2016
Barbano RL.
europepmc   +1 more source

Recombinant versus native botulinum neurotoxin type A: structural and pharmacodynamic comparison

Acta Crystallographica Section F, Volume 82, Issue 11, Page 391-401, November 2026.
For the first time, the recombinant core botulinum neurotoxin type A (BoNT/A) expressed in Escherichia coli and nicked in vitro is shown to be structurally identical to native BoNT/A from Clostridium botulinum, enabling direct activity comparison between the recombinant product and the native toxin.Botulinum neurotoxins (BoNTs) are highly potent ...
Zongren Yao, Lingyi Xu, Yu Lu, Hui Gong, Xiaoyun Sun, Yaokun Zhao, Jinhuan Chen, Liming Yang, Qingqing Chen, Wu Yang   +9 more
wiley   +1 more source

Engineering Botulinum Toxins to Improve and Expand Targeting and SNARE Cleavage Activity. [PDF]

Toxins (Basel), 2018
Fonfria E, Elliott M, Beard M, Chaddock JA, Krupp J.   +4 more
europepmc   +1 more source

Health‐related quality of life and patient‐reported outcome measures in economic evaluation of urological technologies: challenges and opportunities

BJU International, Volume 138, Issue 5, Page 750-758, November 2026.
Objective To examine the role of health‐related quality of life (HRQoL) assessments and patient‐reported outcome measures (PROMs) in the economic evaluation of urological interventions, highlighting methodological challenges, and identifying areas for future development.
Mohammed El Bahnasawi, Charlotte Moss, Netty Kinsella, Kathie Alexina Wong, Mieke Van Hemelrijck   +4 more
wiley   +1 more source

Evaluation of a Multipolar MEMS Based Low‐Power Radiofrequency Device for Pain‐Free Facial Rejuvenation: A Prospective Clinical Study

Journal of Cosmetic Dermatology, Volume 25, Issue 11, November 2026.
ABSTRACT Background Noninvasive radiofrequency (RF) therapy has emerged as a prominent approach for facial rejuvenation due to its ability to stimulate collagen remodeling without epidermal ablation. However, conventional RF systems often rely on high thermal output, posing risks of heat‐induced dermal damage. Objective This study aimed to evaluate the
Rongwei Mao, Shengshuo Yan, Aditi A. Sharma, Tony Shum, Yang Zhang   +4 more
wiley   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Deep Gluteal Syndrome and Persistent Sciatica in a Patient With Unilateral Piriformis Muscle Hypertrophy: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A man of 47 had 6 months of left sciatica without root compression on lumbar imaging. Pelvic CT showed isolated left piriformis hypertrophy, 700 versus 450 mm2. Guided betamethasone injection relieved him within 48 h, sustained at 6 months. Asymmetry and response support, but do not prove, sciatic nerve entrapment.
Najoua Ghani
wiley   +1 more source

Whole‐Exome Sequencing Reveals the Genetic Landscape and Genotype–Phenotype Spectrum of Dystonia in a Chinese Cohort

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Whole‐exome sequencing of 147 Chinese patients with dystonia revealed an overall molecular diagnostic yield of 33.3%, with higher yields in generalized and childhood‐onset cases. The study expands the genotype–phenotype spectrum of established dystonia genes and provides population‐specific evidence to support genetic evaluation and molecular ...
Yiqing Gong, Huirong Peng, Zhao Chen, Jiawei He, Linliu Peng, Qian Jiang, Chunrong Wang, Linlin Wan, Lang He, Yuting Shi, Rong Qiu, Hong Jiang   +11 more
wiley   +1 more source