Efficacy and Safety of Intratympanic Botulinum Toxin Injection on Middle Ear Myoclonic Tinnitus
The Laryngoscope, EarlyView.Intratympanic Botulinum toxin (IT‐BTX) injection appears to be an effective and safe treatment for MEMT, significantly reducing tinnitus‐related symptoms without complications. In a retrospective study of 57 patients, THI scores and VAS measures for loudness, awareness, annoyance, and life impact improved significantly over 6 months.
Ji Hyung Lim +8 more
wiley +1 more source
Bacterial Toxins: Friends or Foes?
Emerging Infectious Diseases, 1999 Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes.
Clare K. Schmitt +2 more
doaj +1 more source
Botulinum toxin therapy: functional silencing of salivary disorders. [PDF]
, 2017 Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary ...
Lovato, A +4 more
core
Cost-Effectiveness of Treating Upper Limb Spasticity Due to Stroke with Botulinum Toxin Type A: Results from the Botulinum Toxin for the Upper Limb after Stroke (BoTULS) Trial [PDF]
, 2012 Stroke imposes significant burdens on health services and society, and as such there is a growing need to assess the cost-effectiveness of stroke treatment to ensure maximum benefit is derived from limited resources.
Christopher Price +16 more
core +3 more sources
Developments in Post-Stroke Spasticity Care with Early Use of Botulinum Toxin A: A Review [PDF]
, 2023 Maria Leila Doquenia
openalex +1 more source
Pediatric Neurology Briefs, 1990 A report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology concludes that local injection of type A botulinum toxin (Botox) is proven as a safe and efficacious modality for the treatment of blepharospasm, cervical dystonia, and hemifacial spasm.
openaire +3 more sources
Validation of an Endoscopic Landmark for Injection of Internal Branch of Superior Laryngeal Nerve
The Laryngoscope, EarlyView.This study validates a transnasal endoscopic approach to target the internal branch of the superior laryngeal nerve (iSLN) via the piriform sinus. Cadaveric analysis showed this method enables precise localization with minimal variability, offering a promising technique for treating laryngeal sensory dysfunction.
Yuki Tanigami +4 more
wiley +1 more source
Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris. [PDF]
, 2005 RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Ellar, David J, Gurkan, Cemal
core +2 more sources
Botulinum toxin type A in chronic neuropathic pain in refractory leprosy
Arquivos de Neuro-PsiquiatriaNeuropathic pain is a chronic syndrome that is difficult to treat and often affects patients with leprosy. Recommended treatment includes the the use of analgesic drugs, codeine, tricyclic antidepressants, neuroleptics, anticonvulsants and thalidomide ...
Emanuel de Jesus Soares de Sousa +4 more
doaj +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
wiley +1 more source