Automated Creak Identifies Laryngeal Dystonia During Conversational Speech
The Laryngoscope, EarlyView.This study evaluated whether automated creak distinguished speakers with adductor laryngeal dystonia (AdLD), muscle tension dysphonia (MTD), and those without voice disorders during conversational speech. Automated creak estimates were able to differentiate speakers with AdLD from MTD and controls with similar performance across different types of ...
Daria A. Dragicevic +13 more
wiley +1 more source
Lasers in Surgery and Medicine, EarlyView.ABSTRACT Background Energy‐based treatments for atrophic acne scars (AAS) in darker skin phototypes must balance efficacy with pigmentary safety. While the nonablative 675‐nm laser has shown promise with minimal risk of adverse effects, prospective data in Asian populations remain limited.
Pinthisa Nisagornsen +6 more
wiley +1 more source
Cleaved intracellular SNARE peptides are implicated in a novel cytotoxicity mechanism of botulinum serotype C [PDF]
, 2013 Recent advances in intracellular protein delivery have enabled more in-depth analyses of cellular functions. A specialized family of SNARE proteases, known as Botulinum Neurotoxins, blocks neurotransmitter exocytosis, which leads to systemic toxicity ...
Arsenault, Jason +5 more
core +1 more source
Botulinum Toxin Efficacy in Upper Limb Tremor: A Systematic Review and Meta‐Analysis
Movement Disorders Clinical Practice, EarlyView.Abstract Background Essential tremor (ET) and dystonic tremor syndrome (DTS) can be treated using botulinum toxin (BoNT) injections. Previous reviews lacked an assessment of the certainty of evidence and focused solely on clinician‐reported outcomes. Additionally, studies have demonstrated interindividual variability in BoNT efficacy. Objective The aim
Iris M. Visser +5 more
wiley +1 more source
Structure of dual receptor binding to botulinum neurotoxin B [PDF]
, 2014 Botulinum neurotoxins are highly toxic, and bind two receptors to achieve their high affinity and specificity for neurons. Here we present the first structure of a botulinum neurotoxin bound to both its receptors.
Berntsson, Ronnie P-A +3 more
core +1 more source
A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways. [PDF]
, 2020 Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization.
Bier, Ethan +4 more
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Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris. [PDF]
, 2005 RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Ellar, David J, Gurkan, Cemal
core +2 more sources
Outbreak of botulism in horses associated with toxin A and D in São Paulo state, Brazil
Pesquisa Veterinária Brasileira: Botulism is a neuromuscular disorder caused by neurotoxins produced by Clostridium botulinum. Equine botulism has been frequently reported worldwide; however, descriptions of cases in South America remain uncommon.
Simone Miyashiro +9 more
doaj +1 more source
Managing Dystonia in Partington Syndrome
Movement Disorders Clinical Practice, EarlyView.Abstract Background Bilateral focal hand dystonia is an almost pathognomonic sign of Partington syndrome, frequently accompanied by intellectual disability and oromotor dyspraxia. However, a few studies have focused on the treatment of this focal dystonia, making patient management uncertain.
Emilie Pichon +13 more
wiley +1 more source
Amylase release from streptolysin O-permeabilized pancreatic acinar cells. Effects of Ca2+, guanosine 5'-[gamma-thio]triphosphate, cyclic AMP, tetanus toxin and botulinum A toxin [PDF]
, 1992 The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O.
Ahnert-Hilger, G. +4 more
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