Results 81 to 90 of about 21,762 (295)
Friends or Foes? Emerging Impacts of Biological Toxins [PDF]
Toxins are substances produced from biological sources (e.g., animal, plants, microorganisms) that have deleterious effects on a living organism. Despite the obvious health concerns of being exposed to toxins, they are having substantial positive impacts
Casewell, N.R. +6 more
core +6 more sources
The Pain in Dystonia Scale (PIDS)—Validation in Craniofacial and Upper Limb Dystonia
ABSTRACT Background Pain is one of the most disabling non‐motor symptoms in adult‐onset isolated dystonia (AOID). The Pain in Dystonia Scale (PIDS) was developed and validated in cervical dystonia. Its applicability to other focal subtypes remains unknown.
Veronica Bruno +24 more
wiley +1 more source
Botulism: life-threatening illness
Introduction. Botulism is a potentially fatal syndrome of diffuse, flaccid paralysis caused by botulinum neurotoxin (BoNT), produced by the bacterium Clostridium botulinum.
Adan Raed ABO ARKIA
doaj
Reply to: Deprescribing after DBS in Dystonia: Promise, Pitfalls, and a Path Forward
Movement Disorders Clinical Practice, EarlyView.
Marcela A. Montiel, Alfonso Fasano
wiley +1 more source
The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares +2 more
wiley +1 more source
Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy +7 more
wiley +1 more source
On Botulinum Neurotoxin Variability
The rapidly growing number of botulinum neurotoxin sequences poses the problem of the possible evolutionary significance of the variability of these superpotent neurotoxins for toxin-producing Clostridium species. To progress in the understanding of this
Cesare Montecucco, Maria Berica Rasotto
doaj +1 more source
Capsaicin protects neuromuscular junctions from the inhibitory effects of botulinum neurotoxin A [PDF]
Within 24 hrs after injecting botulinum neurotoxin A (BoNT/A) into the hindlimb, mice lost the toe spread reflex and developed progressive muscle weakness. At the same time, the compound muscle action potential amplitude decreased. Injection of capsaicin
Baskaran Thyagarajan +5 more
core +1 more source
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Proteomic Methods of Detection and Quantification of Protein Toxins
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Miloslava Duracova +3 more
doaj +1 more source

