Results 51 to 60 of about 14,212 (288)

Harnessing the Membrane Translocation Properties of AB Toxins for Therapeutic Applications

Toxins, 2021
Over the last few decades, proteins and peptides have become increasingly more common as FDA-approved drugs, despite their inefficient delivery due to their inability to cross the plasma membrane.
Numa Piot, F. Gisou van der Goot, Oksana A. Sergeeva   +2 more
doaj   +1 more source

Canned Foods: Evolution, Benefits, and Health Implications of Modern Packaging

Food Safety and Health, EarlyView.
This graphical abstract presents a concise visual overview of canned food technology, highlighting its historical evolution, key benefits, and associated health risks. It integrates timelines, icons, and summary points to clearly communicate advancements in preservation, consumer advantages, and potential safety concerns in a single schematic ...
Shaswati Rout, Priyadarsini Sahoo, Anuprita Ray, Shuvendu Shekhar Mohapatra   +3 more
wiley   +1 more source

Bacterial Toxins: Friends or Foes?

Emerging Infectious Diseases, 1999
Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes.
Clare K. Schmitt, Karen C. Meysick, Alison D. O'Brien   +2 more
doaj   +1 more source

Interrater reliability in pediatric high‐resolution anorectal manometry recordings

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives High‐resolution anorectal manometry (HR‐ARM) is a diagnostic test assessing anorectal neuromuscular function in children with constipation and/or fecal incontinence. Interrater reliability of HR‐ARM in children has not been previously studied. The aim of this study was to assess the interrater reliability of pediatric HR‐ARM studies.
Julia M. J. van der Zande, Marc A. Benninga, Bruno P. Chumpitazi, Anil Darbari, Jose M. Garza, Julie Khlevner, Samuel Nurko, Miguel Saps, Karla Vaz, Sujithra Velayuthan, Md Rejuan Haque, Carlo Di Lorenzo, Peter L. Lu   +12 more
wiley   +1 more source

Adjunctive Botulinum Toxin Type A for Bruxism and Sweat‐Worsened Facial Blistering in Recessive Dystrophic Epidermolysis Bullosa: A Case Series

JEADV Clinical Practice, EarlyView.
Capsule Summary Bruxism and sweat‐induced facial blisters can affect patients with Recessive Dystrophic Epidermolysis Bullosa (RDEB) quality of life (QoL). We present the outcomes of orofacial BTX‐A infiltrations to treat these conditions. Three patients with severe RDEB, bruxism and microstomia received BTX‐A infiltrations (50U‐100U) in masseters and ...
Susanne Krämer, Sebastián Véliz, Gina Pennacchiotti, Fernanda Salazar, María‐Beatriz Méndez   +4 more
wiley   +1 more source

Efficacy and Safety of Low-Dose Intravesical OnabotulinumtoxinA Injections in Female Patients With Detrusor Overactivity With Detrusor Underactivity [PDF]

International Neurourology Journal
Purpose We assessed the effectiveness and safety of using intravesical onabotulinumtoxinA (onabotA; BOTOX) injection with a low dose (75 units) for treating urinary storage symptoms in patients with detrusor overactivity with detrusor underactivity (DODU)
Hyun Seok Na, Chung Lyul Lee, Jae Sung Lim, Ki Hak Song, Ju Hyun Shin, Jong Mok Park, Ji Yong Lee   +6 more
doaj   +1 more source

Trends in Laryngology Fellowship Training: A Survey Study of Graduates and Directors

The Laryngoscope, EarlyView.
A survey study of laryngology fellowship Graduates and Directors reveals overall high level of confidence in preparedness to practice in the care of most laryngologic disorders. Respondents reported less exposure to swallowing disorders in fellowship with resulting lower confidence to practice independently in this area, despite seeing a good ...
Vanessa Torrecillas, Michael M. Johns III, Al Merati, Robbi Kupfer, Robert J. Morrison   +4 more
wiley   +1 more source

How I Do It: The Transtracheal Approach for Awake Cricopharyngeal Botulinum Toxin Injection

The Laryngoscope, EarlyView.
This transtracheal technique for cricopharyngeal botulinum toxin injection is a safe and effective option for chemodenervation of this muscle in the awake patient. Its advantages include reduced risk of toxin spread to intrinsic laryngeal muscles, the ability to administer higher doses of botulinum toxin, improved access to the entire length of the ...
Andrew Tritter, Alexander Simko, Karim Asi   +2 more
wiley   +1 more source

Botulinum toxin type A for painful diabetic neuropathy: an open-label study

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background A large proportion of painful diabetic neuropathy cases either do not respond or are intolerant to the currently available oral and physical therapies.
Shahinaz Helmy, Tamer Emara, Amr Abdel Menem   +2 more
doaj   +1 more source

Automated Creak Identifies Laryngeal Dystonia During Conversational Speech

The Laryngoscope, EarlyView.
This study evaluated whether automated creak distinguished speakers with adductor laryngeal dystonia (AdLD), muscle tension dysphonia (MTD), and those without voice disorders during conversational speech. Automated creak estimates were able to differentiate speakers with AdLD from MTD and controls with similar performance across different types of ...
Daria A. Dragicevic, Cara E. Sauder, Daniel P. Buckley, Laura E. Toles, Lauren F. Tracy, J. Pieter Noordzij, Gregory A. Grillone, Ted Mau, John Paul Giliberto, Tanya K. Meyer, Albert L. Merati, Tanya L. Eadie, Cara E. Stepp, Katherine L. Marks   +13 more
wiley   +1 more source