Results 81 to 90 of about 59,041 (264)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Two-parameter locus of boundary crisis: mind the gaps!

open access: yes, 2010
Boundary crisis is a mechanism for destroying a chaotic attractor when one parameter is varied. In a two-parameter setting the locus of boundary crisis is associated with curves of homo- or heteroclinic tangency bifurcations of saddle periodic orbits. It
Osinga, Hinke M, Rankin, J
core  

On the longtime behavior of a viscous Cahn–Hilliard system with convection and dynamic boundary conditions [PDF]

open access: yes, 2018
In this paper, we study the longtime asymptotic behavior of a phase separation process occurring in a three-dimensional domain containing a fluid flow of given velocity. This process is modeled by a viscous convective Cahn–Hilliard system, which consists
Sprekels, Jürgen   +2 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Minimal thinness with respect to the Schrödinger operator and its applications on singular Schrödinger-type boundary value problems

open access: yesBoundary Value Problems, 2019
The application of the new criteria for minimally thin sets with respect to the Schrödinger operator to an approximate solution of singular Schrödinger-type boundary value problems are discussed in this study.
Bo Meng
doaj   +1 more source

Dynamic behavior of frame structures by boundary integral procedures

open access: yes, 2015
The Boundary Element Method is applied to synthesize a set of Boundary Integral Equations representing the uncoupled axial and flexural dynamic behavior of rectilinear Bernoulli-Euler beam elements in the frequency domain.
Barretto, SFA, Neto, ED, Pavanello, R
core  

Effect of Soil Box Boundary Conditions on Dynamic Behavior of Model Soil in 1 g Shaking Table Test

open access: yesApplied Sciences, 2020
In order to evaluate the effects of soil box boundary conditions on the dynamic soil behavior, the Rigid Box (RB) and the Laminar Shear box (LSB) were constructed and 1 g shaking table tests were carried out for various boundary conditions.
Hoyeon Kim   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Gurtin and Murdoch's surface effect on the elastic behavior of an elastic half space subjected to body forces

open access: yes, 2022
Surface effect have significant influence on mechanical behavior of material at nano scale. Classical solutions have limitations in predicting the micromechanics of materials due to the neglect of surface effect. This paper examines a generalized Mindlin'
Wang, SL, CHEN, X, Yue, QZQ
core   +1 more source

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