Results 71 to 80 of about 1,137,021 (285)

STRUCTURAL SHAPE OPTIMIZATION BY ISOGEOMETRIC BOUNDARY ELEMENT METHOD

Jixie qiangdu, 2019
In Isogeometric boundary element method（IGA-BEM）, Non-Uniform Rational B-Splines（NURBS） which are used for describing the geometric boundary in a computer-aided geometric design（CAGD） are employed as shape functions of Boundary Element Method.
SUN ShaoHui, YIN ShuoHui
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Isogeometric Fast Multipole Boundary Element Method Based on Burton-Miller Formulation for 3D Acoustic Problems

Archives of Acoustics, 2019
An isogeometric boundary element method is applied to simulate wave scattering problems governed by the Helmholtz equation. The NURBS (non-uniform rational B-splines) widely used in the CAD (computer aided design) field is applied to represent the ...
Leilei CHEN, Wenchang ZHAO, Cheng LIU, Haibo CHEN, Steffen MARBURG   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

ANALISA ELASTISITAS DENGAN BOUNDARY ELEMENT

Media Mesin, 2016
Dalam tulisan ini, analisa elastisitas dengan  boundary element method disampaikan. Perumusan-perumusan boundary element method juga diperkeknalkan. Untuk menyelesaikan persamaan yang didapatkan integrasi numerik diterapkan.
Supriyono Supriyono
doaj  

Prediction of waterjet excited underwater radiated noise by boundary element method

Zhongguo Jianchuan Yanjiu, 2017
Aiming to mitigate impact of the uncertain boundary conditions setting on the underwater radiated noise calculation, the numerical prediction method of calculating the underwater radiated noise of a waterjet by the one-step boundary element method was ...
LIU Qiang, WANG Yongsheng, ZHANG Mingyu, YI Wenbin, WEI Yingsan   +4 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Two-dimensional acoustic analysis using Taylor expansion-based boundary element method

Frontiers in Physics
The use of boundary elements in two-dimensional acoustic analysis is presented in this study, along with a detailed explanation of how to derive the final discrete equations from the fundamental fluctuation equations.
Yan Yang, Guang Lei, Guang Lei, Sen Yang, Sen Yang, Yanming Xu   +5 more
doaj   +1 more source

Regularized singular boundary method for groundwater flow in a cofferdam

MATEC Web of Conferences, 2018
The boundary integral methods form one group of methods for solving differential equations. The boundary element method (BEM) is the basic method of this group.
Mužík Juraj, Bulko Roman
doaj   +1 more source