Results 121 to 130 of about 215,554 (316)

Studying boundary elements’ behaviour using masonry walls built with high-resistance bricks

open access: yesIngeniería e Investigación, 2006
This research was aimed at studying the behaviour of masonry walls built with and without boundary elements at both ends when sublected to monotonic and cyclic lateral loads.
Juan Carlos Restrepo Mejía   +1 more
doaj  

Numerical solution and spectrum of boundary-domain integral equation for the Neumann BVP with variable coefficient

open access: yes, 2012
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 Taylor & Francis.In this paper, a numerical implementation of a direct united boundary-domain integral equation (BDIE ...
Mikhailov, SE, Mohamed, NA
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

APPLYING BOUNDARY ELEMENT METHOD TO SOLVE THE HEAT CONDUCTION PROBLEMS USING CONSTANT ELEMENT

open access: yesJournal of Engineering and Sustainable Development, 2015
In this work two-dimensional boundary element method (BEM) using constant element is mathematically and numerically investigated and applied to solve differential equations of the heat conduction problems and temperature distribution of solid bodies to ...
Saad Najeeb Shehab
doaj  

Hybrid stress and analytical functions for analysis of thin plates bending

open access: yesLatin American Journal of Solids and Structures
In this paper, two efficient elements for analyzing thin plate bending are proposed. They are a triangular element (THS) and a quadrilateral element (QHS), which have 9 and 12 degrees of freedom, respectively.
Mohammad Rezaiee-Pajand, Mohammad Karkon
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Integrity of a heterochromatic domain ensured by its boundary elements. [PDF]

open access: yesProc Natl Acad Sci U S A, 2020
Charlton SJ, Jørgensen MM, Thon G.
europepmc   +1 more source

DRBEM formulation for transient Stokes flow with slip boundary condition [PDF]

open access: yes, 2016
In this study, the effect of linear and nonlinear slip boundary conditions on the flow of a slow viscous fluid is investigated numerically. The boundary integral representation of the transient Stokes equations is given in primitive variables form.
Wrobel, LC, Gumgum, S
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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