Results 131 to 140 of about 215,554 (316)
Precise boundary element method for non-horizontally layered foundations and its applications
Yantu gongcheng xuebaoA new boundary element method (BEM) is developed for accurately calculating the additional stresses and settlements in non-horizontally layered foundations.
XIAO Sha 1 , YUE Zhongqi 2, 3
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 2006 A quasi-static mixed boundary value problem of incremental elasto-plasticity for a continuously inhomogeneous body is considered. Using the two-operator Green–Betti formula and the fundamental solution of a reference homogeneous linear elasticity problem,
Mikhailov, SE
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Analysis of two-operator boundary-domain integral equations for variable-coefficient mixed BVP
, 2011 This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 Steklov Mathematical Institute RAS.Applying the two-operator approach, the mixed (Dirichlet–Neumann) boundary value ...
Mikhailov, SE, Ayele, TG
core
, 2005 Mixed boundary-value Problems (BVPs) for a second-order quasi-linear elliptic partial differential equation with variable coefficients dependent on the unknown solution and its gradient are considered.
Mikhailov, SE, S. E. Mikhailov
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A boundary element model for nonlinear viscoelasticity
, 2009 The boundary element methodology is applied to the analysis of non-linear viscoelastic solids. Theadopted non-linear model uses the same relaxation moduli as the respective linear relations but with a time shiftdepending on the volumetric strain ...
Syngellakis, S., Wu, J.
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