Results 141 to 150 of about 215,554 (316)

Modeling of fluid flow in periodic cell with porous cylinder using a boundary element method [PDF]

, 2016
© 2016 Elsevier Ltd. All rights reserved.The problem of viscous incompressible flow past a periodic array of porous cylinders (a model of flow in an aerosol filter) is solved. The approximate periodic cell model of Kuwabara is used to formulate the fluid
Mardanov R., Zaripov S., Dunnett S.
core  

Analysis of segregated boundary-domain integral equations for variable-coefficient problems with cracks

, 2010
This is the pre-print version of the article. The official published version can be obtained from the link below - Copyright @ 2011 Wiley-BlackwellSegregated direct boundary-domain integral equation (BDIE) systems associated with mixed, Dirichlet and ...
S.E. Mikhailov, Mikhailov, SE, O. Chkadua, Natroshvili, D, Chkadua, O, D. Natroshvili   +5 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Charge Particle Optics Simulation Utilizing Hamiltonian Mechanics Perturbation Expansion and Boundary Elements Field Computation [PDF]

BIO Web of Conferences
Lubk Axel, Houdellier Florent, Müller Heiko, Uhlemann Stephan   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A graph model to describe the network connectivity of trabecular plates and rods

Frontiers in Bioengineering and Biotechnology
Introduction: The trabecular network is perceived as a collection of interconnected plate- (P) and rod-like (R) elements. Previous research has highlighted how these elements and their connectivity influence the mechanical properties of bone, yet further
Matthias Walle, Matthias Walle, Diana Yeritsyan, Mohammadreza Abbasian, Ramin Oftadeh, Ralph Müller, Ara Nazarian, Ara Nazarian   +7 more
doaj   +1 more source

Modeling of fluid flow in periodic cell with porous cylinder using a boundary element method

, 2020
© 2016 Elsevier Ltd. All rights reserved.The problem of viscous incompressible flow past a periodic array of porous cylinders (a model of flow in an aerosol filter) is solved. The approximate periodic cell model of Kuwabara is used to formulate the fluid
Mardanov R., Zaripov S., Dunnett S.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Boundary elements for non-linear elasticity

, 2003
A boundary element technique is employed to analyze perturbations in terms of small elastic deformations superimposed upon a given homogeneous strain. Plane strain deformations are considered of an incompressible hyperelastic solid within the elliptic ...
CAPUANI, Domenico, Bigoni D., Brun M.
core