Results 91 to 100 of about 13,856,788 (331)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Darboux Transformation of the Green Function for the Dirac Equation with the Generalized Potential

, 2007
We consider the Darboux transformation of the Green functions of the regular boundary problem of the one-dimensional stationary Dirac equation. We obtained the Green functions of the transformed Dirac equation with the initial regular boundary conditions.
Bagrov V. G., Darboux G., Darboux G., EKATERINA POZDEEVA, Pozdeeva E. O., Pupasov A. M., Song D.-Y., Witten E.   +7 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Numerical Reconstruction of the Source in Dynamical Boundary Condition of Laplace’s Equation

Axioms
In this work, we consider Cauchy-type problems for Laplace’s equation with a dynamical boundary condition on a part of the domain boundary. We construct a discrete-in-time, meshless method for solving two inverse problems for recovering the space–time ...
Miglena N. Koleva, Lubin G. Vulkov
doaj   +1 more source

Bounds on the curvature for functions with bounded boundary rotation of order 1−b

International Journal of Mathematics and Mathematical Sciences, 1986
Let Vk(1−b), k≥2 and b≠0 real, denotes the class of locally univalent analytic functions f(z)=z+∑n=2∞anzn in D={z:|z|
M. A. Nasr
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Evaluating Scale‐Aware Boundary Layer Similarity Functions and Their Mechanisms in Tropical Cyclone Modeling Using Idealized Large‐Eddy Simulations

Geophysical Research Letters
Accurate representation of scale‐aware boundary layer similarity functions at gray‐zone resolutions is crucial for advancing boundary layer schemes.
Yinjun Wang, Hongxiong Xu, Xiangde Xu, Shaofeng Liu, Chunsheng Zhang, Yanfeng Huo   +5 more
doaj   +1 more source

Boundary Ground Ring in 2D String Theory

, 2003
The 2D quantum gravity on a disc, or the non-critical theory of open strings, is known to exhibit an integrable structure, the boundary ground ring, which determines completely the boundary correlation functions.
Aganagic, Alexandrov, Alexandrov, Belavin, Bershadsky, Bershadsky, Di Francesco, Di Francesco, Dijkgraaf, Dijkgraaf, Dorn, Dotsenko, Douglas, Fateev, Ginsparg, Goulian, Govindarajan, Govindarajan, Higuchi, Hosomichi, Imbimbo, Ivan K. Kostov, Jevicki, Kachru, Kazakov, Kazakov, Kharchev, Klebanov, Klebanov, Klebanov, Klebanov, Kostov, Kostov, Kostov, Kostov, Kostov, Kostov, Kostov, Kostov, Kostov, Kostov, Kostov, Kutasov, Martinec, McGreevy, McGreevy, Petkova, Polchinski, Ponsot, Recknagel, Schomerus, Seiberg, Sen, Tanii, Tanii, Teschner, Teschner, Witten, Witten, Yin, Zamolodchikov, Zamolodchikov   +61 more
core   +5 more sources