Results 101 to 110 of about 13,856,788 (331)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Single-particle states in spherical Si/SiO$_2$ quantum dots
, 2007 We calculate ground and excited electron and hole levels in spherical Si quantum dots inside SiO$_2$ in a multiband effective mass approximation. Luttinger Hamiltonian is used for holes and the strong anisotropy of the conduction electron effective mass ...
A. A. Prokofiev +14 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Boundary-nonregular functions in the disc algebra and in holomorphic Lipschitz spaces [PDF]
, 2018 We prove in this paper the existence of dense linear subspaces in the classical holomorphic Lipschitz spaces in the disc all of whose non-null functions are nowhere differentiable at the boundary.
Bernal González, Luis +3 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Two-point boundary correlation functions of dense loop models
SciPost Physics, 2018 We investigate six types of two-point boundary correlation functions in the dense loop model. These are defined as ratios $Z/Z^0$ of partition functions on the $m\times n$ square lattice, with the boundary condition for $Z$ depending on two points $x$
Alexi Morin-Duchesne, Jesper Lykke Jacobsen
doaj +1 more source
On selecting the critical boundary functions in group-sequential trials with two time-to-event outcomes. [PDF]
Contemp Clin Trials, 2021 Hamasaki T +3 more
europepmc +1 more source
A Boundary Theorem for Tsuji Functions [PDF]
Nagoya Mathematical Journal, 1967 Let D denote the unit disc | z | <1, C the unit circle | z | = 1 and Cr the circle | z| = r. Corresponding to any function w(z) meromorphic in D we denote by w*(z) the spherical derivative
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source