Results 81 to 90 of about 6,501,456 (385)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Ten Years of Boundary-Layer and Wind-Power Meteorology at Høvsøre, Denmark

open access: yesBoundary-layer Meteorology, 2015
Operational since 2004, the National Centre for Wind Turbines at Høvsøre, Denmark has become a reference research site for wind-power meteorology. In this study, we review the site, its instrumentation, observations, and main research programs.
A. Peña   +8 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Modeling Ozone Source Apportionment and Performing Sensitivity Analysis in Summer on the North China Plain

open access: yesAtmosphere, 2020
In recent years, air quality issues due to fine particulate matter have been sufficiently treated. However, ozone (O3) has now become the primary pollutant in summer on the North China Plain (NCP).
Yujing Zhang   +8 more
doaj   +1 more source

Boundary Layer

open access: yes, 2022
AbstractThe Prandtl’s equations for laminar boundary layer are obtained via dimensional analysis. The case of the flat plate is treated as a suitable example for the development of the boundary layer on a simple geometry. Various thicknesses are introduced. The integration of Prandtl’s equation across the boundary layer produces the von Kármán integral
openaire   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

The ISSI international study team on the martian PBL – status report and plan [PDF]

open access: yes, 2008
Dynamical processes in the Martian boundary layer provide the means of communication between surface ice deposits and the free atmosphere, and the means of lifting dust from the surface.
Galperin, B.   +13 more
core  

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